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- 抗原 See all CD73 (NT5E) 抗体
- CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD73 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of NT5E expressed in E. coli.
- 克隆位点
- 1D7
- 亚型
- IgG1
- Top Product
- Discover our top product NT5E Primary Antibody
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- 应用备注
- ELISA: 1:10000, IHC: 1:200 - 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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Effects of ecto-5'-nucleotidase on human breast cancer cell growth in vitro and in vivo." in: Oncology reports, Vol. 17, Issue 6, pp. 1341-6, (2007) (PubMed).
: "Extracellular adenine nucleotides metabolism in astrocyte cultures from different brain regions." in: Neurochemistry international, Vol. 43, Issue 7, pp. 621-8, (2003) (PubMed).
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Effects of ecto-5'-nucleotidase on human breast cancer cell growth in vitro and in vivo." in: Oncology reports, Vol. 17, Issue 6, pp. 1341-6, (2007) (PubMed).
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- 抗原
- CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
- 别名
- NT5E (NT5E 产品)
- 别名
- CALJA antibody, CD73 antibody, E5NT antibody, NT antibody, NT5 antibody, NTE antibody, eN antibody, eNT antibody, zgc:63784 antibody, NT5E antibody, MGC114869 antibody, PSPTO2277 antibody, 2210401F01Rik antibody, AI447961 antibody, Nt5 antibody, 5'-nucleotidase ecto antibody, 5'-nucleotidase, ecto (CD73) antibody, 5'-nucleotidase antibody, 5' nucleotidase, ecto antibody, NT5E antibody, nt5e antibody, nt5e.S antibody, PSPTO_2277 antibody, CBU_1233 antibody, MCA1322 antibody, Nt5e antibody
- 背景
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Description: 5'-nucleotidase, ecto (NT5E), also known as CD73 (Cluster of Differentiation 73). Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase, EC 3.1.3.5) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases (e.g., see MIM 102700, MIM 300300). Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate.
Aliases: eN, NT5, CD73
- 分子量
- 70 kDa
- 基因ID
- 4907
- HGNC
- 4907
- 途径
- Synaptic Membrane, Ribonucleoside Biosynthetic Process
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