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NME1 抗体

NME1 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 4B2 unconjugated
产品编号 ABIN969317
发货至: 中国
  • 抗原 See all NME1 抗体
    NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))
    适用
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    宿主
    • 93
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    小鼠
    克隆类型
    • 95
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    单克隆
    标记
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    This NME1 antibody is un-conjugated
    应用范围
    • 98
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human NME1 expressed in E. coli.
    克隆位点
    4B2
    亚型
    IgG1
    Top Product
    Discover our top product NME1 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Treharne, Giles Best, Mehta: "Transglutaminase 2 and nucleoside diphosphate kinase activity are correlated in epithelial membranes and are abnormal in cystic fibrosis." in: FEBS letters, Vol. 583, Issue 17, pp. 2789-92, (2009) (PubMed).

    Egistelli, Chichiarelli, Gaucci, Eufemi, Schininà, Giorgi, Lascu, Turano, Giartosio, Cervoni: "IFI16 and NM23 bind to a common DNA fragment both in the P53 and the cMYC gene promoters." in: Journal of cellular biochemistry, Vol. 106, Issue 4, pp. 666-72, (2009) (PubMed).

    Lee, Jeong, Kim, Song, Kang, Lee: "Multiple functions of Nm23-H1 are regulated by oxido-reduction system." in: PLoS ONE, Vol. 4, Issue 11, pp. e7949, (2009) (PubMed).

  • 抗原
    NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))
    别名
    NME1 (NME1 产品)
    别名
    AWD antibody, GAAD antibody, NB antibody, NBS antibody, NDKA antibody, NDPK-A antibody, NDPKA antibody, NM23 antibody, NM23-H1 antibody, AL024257 antibody, NM23-M1 antibody, NM23A antibody, NDPK-Z1 antibody, NM23-B antibody, NM23-Z1 antibody, ndpkz1 antibody, nm23b antibody, nme1 antibody, nme2 antibody, nme2b1 antibody, NME1 antibody, NME1-NME2 antibody, NM23-C1 antibody, ndpk-b antibody, ndpkb antibody, nm23-h2 antibody, nm23ndk antibody, puf antibody, NBR-A antibody, NBR-B antibody, NME1-1 antibody, nm23ndk-a antibody, NDK I antibody, NDPK I antibody, T30A10.80 antibody, T30A10_80 antibody, NDP kinase I antibody, NME/NM23 nucleoside diphosphate kinase 1 antibody, NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1 antibody, non-metastatic cells 1, protein (NM23A) expressed in antibody, NME/NM23 nucleoside diphosphate kinase 2 S homeolog antibody, NME/NM23 nucleoside diphosphate kinase 2 L homeolog antibody, nucleoside diphosphate kinase antibody, nucleoside diphosphate kinase 1 antibody, NME1 antibody, Nme1 antibody, nme2b.1 antibody, nme2.S antibody, nme2.L antibody, LOC547870 antibody, NDPK1 antibody, LOC107790563 antibody
    背景

    Description: non-metastatic cells 1,protein,with a nm23 nucleoside diphosphate kinase gene family,involved in the phosphorylation of nucleoside diphosphates,with a reduced expression in tumor progression to the metastatic phenotype,mutated in agressive neuroblastoma,expressed in lung carcinoma cell lines not in normal lung,pyrimidine biosynthetic pathway. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. Has tumor metastasis-suppressive capacity.Tissue specificity: Isoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation. Isoform 3 is ubiquitously expressed.

    Aliases: NB, AWD, NBS, GAAD, NM23, NDPKA, NDPK-A, NM23-H1, NME1

    分子量
    17 kDa
    基因ID
    4830
    HGNC
    4830
    途径
    Apoptosis, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process
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