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- 抗原 See all NME1 抗体
- NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NME1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 原理
- NME1 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human NME1 expressed in E. Coli.
- 克隆位点
- 4B2
- 亚型
- IgG1
- Top Product
- Discover our top product NME1 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Transglutaminase 2 and nucleoside diphosphate kinase activity are correlated in epithelial membranes and are abnormal in cystic fibrosis." in: FEBS letters, Vol. 583, Issue 17, pp. 2789-92, (2009) (PubMed).
: "IFI16 and NM23 bind to a common DNA fragment both in the P53 and the cMYC gene promoters." in: Journal of cellular biochemistry, Vol. 106, Issue 4, pp. 666-72, (2009) (PubMed).
: "Multiple functions of Nm23-H1 are regulated by oxido-reduction system." in: PLoS ONE, Vol. 4, Issue 11, pp. e7949, (2009) (PubMed).
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Transglutaminase 2 and nucleoside diphosphate kinase activity are correlated in epithelial membranes and are abnormal in cystic fibrosis." in: FEBS letters, Vol. 583, Issue 17, pp. 2789-92, (2009) (PubMed).
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- 抗原
- NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))
- 别名
- NME1 (NME1 产品)
- 别名
- AWD antibody, GAAD antibody, NB antibody, NBS antibody, NDKA antibody, NDPK-A antibody, NDPKA antibody, NM23 antibody, NM23-H1 antibody, AL024257 antibody, NM23-M1 antibody, NM23A antibody, NDPK-Z1 antibody, NM23-B antibody, NM23-Z1 antibody, ndpkz1 antibody, nm23b antibody, nme1 antibody, nme2 antibody, nme2b1 antibody, NME1 antibody, NME1-NME2 antibody, NM23-C1 antibody, ndpk-b antibody, ndpkb antibody, nm23-h2 antibody, nm23ndk antibody, puf antibody, NBR-A antibody, NBR-B antibody, NME1-1 antibody, nm23ndk-a antibody, NDK I antibody, NDPK I antibody, T30A10.80 antibody, T30A10_80 antibody, NDP kinase I antibody, NME/NM23 nucleoside diphosphate kinase 1 antibody, NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1 antibody, non-metastatic cells 1, protein (NM23A) expressed in antibody, NME/NM23 nucleoside diphosphate kinase 2 S homeolog antibody, NME/NM23 nucleoside diphosphate kinase 2 L homeolog antibody, nucleoside diphosphate kinase antibody, nucleoside diphosphate kinase 1 antibody, NME1 antibody, Nme1 antibody, nme2b.1 antibody, nme2.S antibody, nme2.L antibody, LOC547870 antibody, NDPK1 antibody, LOC107790563 antibody
- 背景
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Description: non-metastatic cells 1,protein,with a nm23 nucleoside diphosphate kinase gene family,involved in the phosphorylation of nucleoside diphosphates,with a reduced expression in tumor progression to the metastatic phenotype,mutated in agressive neuroblastoma,expressed in lung carcinoma cell lines not in normal lung,pyrimidine biosynthetic pathway. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. Has tumor metastasis-suppressive capacity.Tissue specificity: Isoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation. Isoform 3 is ubiquitously expressed.
Aliases: NB, AWD, NBS, GAAD, NM23, NDPKA, NDPK-A, NM23-H1, NME1
- 分子量
- 17kDa
- 基因ID
- 4830
- HGNC
- 4830
- UniProt
- P15531
- 途径
- Apoptosis, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process
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