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NFKBIB 抗体

NFKBIB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7B4 unconjugated
产品编号 ABIN969314
发货至: 中国
  • 抗原 See all NFKBIB 抗体
    NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
    适用
    • 113
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    • 1
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    宿主
    • 105
    • 9
    小鼠
    克隆类型
    • 98
    • 16
    单克隆
    标记
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    This NFKBIB antibody is un-conjugated
    应用范围
    • 84
    • 40
    • 30
    • 28
    • 27
    • 19
    • 11
    • 7
    • 6
    • 2
    • 1
    Western Blotting (WB), ELISA
    原理
    NFKBIB Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human NFKBIB expressed in E. Coli.
    克隆位点
    7B4
    亚型
    IgG1
    Top Product
    Discover our top product NFKBIB Primary Antibody
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Yerges, Klei, Cauley, Roeder, Kammerer, Moffett, Ensrud, Nestlerode, Marshall, Hoffman, Lewis, Lang, Barrett-Connor, Ferrell, Orwoll, Zmuda: "High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 12, pp. 2039-49, (2009) (PubMed).

    Chen, Vallee, Wu, Vu, Sondek, Ghosh: "Inhibition of NF-kappaB activity by IkappaBbeta in association with kappaB-Ras." in: Molecular and cellular biology, Vol. 24, Issue 7, pp. 3048-56, (2004) (PubMed).

    Abid, Schoots, Spokes, Wu, Mawhinney, Aird: "Vascular endothelial growth factor-mediated induction of manganese superoxide dismutase occurs through redox-dependent regulation of forkhead and IkappaB/NF-kappaB." in: The Journal of biological chemistry, Vol. 279, Issue 42, pp. 44030-8, (2004) (PubMed).

  • 抗原
    NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
    别名
    NFKBIB (NFKBIB 产品)
    别名
    NFKBIB antibody, IKB-beta antibody, IKappaBbeta antibody, IkB antibody, IkBb antibody, IKBB antibody, TRIP9 antibody, NFKB inhibitor beta antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta antibody, NFKBIB antibody, Nfkbib antibody
    背景

    Description: Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.Tissue specificity: Expressed in all tissues examined.

    Aliases: IKBB, TRIP9, NFKBIB

    分子量
    45kDa
    基因ID
    4793
    HGNC
    4793
    UniProt
    Q15653
    途径
    NF-kappaB Signaling, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades
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