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- 抗原 See all NFKBIB 抗体
- NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NFKBIB antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- NFKBIB Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human NFKBIB expressed in E. Coli.
- 克隆位点
- 7B4
- 亚型
- IgG1
- Top Product
- Discover our top product NFKBIB Primary Antibody
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- 应用备注
- ELISA: 1/10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 12, pp. 2039-49, (2009) (PubMed).
: "Inhibition of NF-kappaB activity by IkappaBbeta in association with kappaB-Ras." in: Molecular and cellular biology, Vol. 24, Issue 7, pp. 3048-56, (2004) (PubMed).
: "Vascular endothelial growth factor-mediated induction of manganese superoxide dismutase occurs through redox-dependent regulation of forkhead and IkappaB/NF-kappaB." in: The Journal of biological chemistry, Vol. 279, Issue 42, pp. 44030-8, (2004) (PubMed).
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High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 12, pp. 2039-49, (2009) (PubMed).
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- 抗原
- NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
- 别名
- NFKBIB (NFKBIB 产品)
- 别名
- NFKBIB antibody, IKB-beta antibody, IKappaBbeta antibody, IkB antibody, IkBb antibody, IKBB antibody, TRIP9 antibody, NFKB inhibitor beta antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta antibody, NFKBIB antibody, Nfkbib antibody
- 背景
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Description: Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.Tissue specificity: Expressed in all tissues examined.
Aliases: IKBB, TRIP9, NFKBIB
- 分子量
- 45kDa
- 基因ID
- 4793
- HGNC
- 4793
- UniProt
- Q15653
- 途径
- NF-kappaB Signaling, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades
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