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NCOR1 抗体 (AA 1-192)

NCOR1 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 7A7A9 unconjugated
产品编号 ABIN969310
发货至: 中国
  • 抗原 See all NCOR1 抗体
    NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))
    抗原表位
    • 15
    • 9
    • 8
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-192
    适用
    • 56
    • 22
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 52
    • 3
    • 1
    • 1
    小鼠
    克隆类型
    • 57
    单克隆
    标记
    • 28
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NCOR1 antibody is un-conjugated
    应用范围
    • 30
    • 21
    • 19
    • 13
    • 13
    • 11
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    原理
    NCOR1 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of NCOR1 (aa1-192) expressed in E. Coli.
    克隆位点
    7A7A9
    亚型
    IgG1
    Top Product
    Discover our top product NCOR1 Primary Antibody
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Atsumi, Tomita, Kiyoi, Naoe: "Histone deacetylase 3 (HDAC3) is recruited to target promoters by PML-RARalpha as a component of the N-CoR co-repressor complex to repress transcription in vivo." in: Biochemical and biophysical research communications, Vol. 345, Issue 4, pp. 1471-80, (2006) (PubMed).

    Zhang, Yoon, Wong: "JMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human transcription factor achaete scute-like homologue 2 (ASCL2/Hash2)." in: Molecular and cellular biology, Vol. 25, Issue 15, pp. 6404-14, (2005) (PubMed).

  • 抗原
    NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))
    别名
    NCOR1 (NCOR1 产品)
    别名
    ncor antibody, zgc:56355 antibody, 5730405M06Rik antibody, A230020K14Rik antibody, N-CoR antibody, RIP13 antibody, Rxrip13 antibody, mKIAA1047 antibody, N-CoR1 antibody, TRAC1 antibody, hN-CoR antibody, nuclear receptor corepressor 1 antibody, nuclear receptor co-repressor 1 antibody, nuclear receptor corepressor 1 pseudogene antibody, nuclear receptor corepressor 1 S homeolog antibody, ncor1 antibody, NCOR1 antibody, CpipJ_CPIJ002507 antibody, LOC100343278 antibody, Ncor1 antibody, ncor1.S antibody
    背景

    Description: NCOR1: Nuclear receptor co-repressor 1. This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.

    Aliases: N-CoR, TRAC1, hN-CoR

    基因ID
    9611
    HGNC
    9611
    UniProt
    O75376
    途径
    Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process
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