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MYL3/CMLC1 抗体

MYL3 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 3F8 unconjugated
产品编号 ABIN969303
发货至: 中国
  • 抗原 See all MYL3/CMLC1 (MYL3) 抗体
    MYL3/CMLC1 (MYL3) (Myosin, Light Chain 3 (MYL3))
    适用
    • 42
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    宿主
    • 40
    • 4
    小鼠
    克隆类型
    • 41
    • 2
    单克隆
    标记
    • 27
    • 3
    • 2
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    This MYL3/CMLC1 antibody is un-conjugated
    应用范围
    • 36
    • 23
    • 23
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of MYL3 expressed in E. coli.
    克隆位点
    3F8
    亚型
    IgG1
    Top Product
    Discover our top product MYL3 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Haase, Dobbernack, Tünnemann, Karczewski, Cardoso, Petzhold, Schlegel, Lutter, Pierschalek, Behlke, Morano: "Minigenes encoding N-terminal domains of human cardiac myosin light chain-1 improve heart function of transgenic rats." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 20, Issue 7, pp. 865-73, (2006) (PubMed).

    Xie, Huang, Huang, Zhou, Gong: "The functional domains of human ventricular myosin light chain 1." in: Biophysical chemistry, Vol. 106, Issue 1, pp. 57-66, (2003) (PubMed).

  • 抗原
    MYL3/CMLC1 (MYL3) (Myosin, Light Chain 3 (MYL3))
    别名
    MYL3 (MYL3 产品)
    别名
    CMD1S antibody, CMH1 antibody, MPD1 antibody, MYHCB antibody, SPMD antibody, SPMM antibody, B-MHC antibody, MyHC-I antibody, Myhc-b antibody, Myhcb antibody, beta-MHC antibody, MLC1s antibody, MLC1v antibody, Mylc antibody, VLC1 antibody, Mylc1v antibody, CMH8 antibody, MLC1SB antibody, MLC1V antibody, mlc1v antibody, myl3-a antibody, myl3-b antibody, myl3.L antibody, zgc:103441 antibody, myosin heavy chain 7 antibody, myosin, heavy polypeptide 7, cardiac muscle, beta antibody, myosin, light polypeptide 3 antibody, myosin light chain 3 antibody, myosin light chain 3 S homeolog antibody, cardiac myosin light chain-1 antibody, MYH7 antibody, Myh7 antibody, Myl3 antibody, MYL3 antibody, myl3.S antibody, cmlc1 antibody
    背景

    Description: Myosins are a large superfamily of motor proteins that move along actin filaments, while hydrolyzing ATP. Myosin is the major component of thick muscle filaments, and is a long asymmetric molecule containing a globular head and a long tail. The molecule consists of two heavy chains and four light chains. Activation of smooth and cardiac muscle primarily involves pathways which increase calcium and myosin phosphorylation resulting in contraction. Myosin light chain phosphatase acts to regulate muscle contraction by dephosphorylating activated myosin light chain. MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Human myosin light chain has clinical application as a cardiac marker. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy.

    Aliases: CMH8, VLC1, MLC1V, MLC1SB

    分子量
    22 kDa
    基因ID
    4634
    HGNC
    4634
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