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- 抗原 See all MSH6 抗体
- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MSH6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- MSH6 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human MSH6 expressed in E. Coli.
- 克隆位点
- 5B11
- 亚型
- IgG1
- Top Product
- Discover our top product MSH6 Primary Antibody
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- 应用备注
- ELISA: 1/10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1beta secretion." in: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 34531-7, (2009) (PubMed).
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Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1beta secretion." in: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 34531-7, (2009) (PubMed).
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- 抗原
- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
- 别名
- MSH6 (MSH6 产品)
- 背景
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Description: This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. ,
Aliases: GTBP, HSAP, HNPCC5
- 分子量
- 160kDa
- 基因ID
- 2956
- HGNC
- 2956
- UniProt
- P52701
- 途径
- DNA Damage Repair, Chromatin Binding, Production of Molecular Mediator of Immune Response
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