MLL/KMT2A 抗体 (AA 3751-3968)
(3 references)-
- 抗原 See all MLL/KMT2A (MLL) 抗体
- MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))
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抗原表位
- AA 3751-3968
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MLL/KMT2A antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA
- 原理
- MLL Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of MLL (aa3751-3968) expressed in E. Coli.
- 克隆位点
- 10F8D7
- 亚型
- IgG1
- Top Product
- Discover our top product MLL Primary Antibody
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anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 3850-3900) antibody
MLL 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 801-956) antibodyMLL 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4A5A12 unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 2829-2883) antibodyMLL 适用: 人, 小鼠 WB, ChIP, ICC, ChIP-seq, IF 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 3561-3670) antibodyMLL 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 3879-3908), (C-Term) antibodyMLL 适用: 人 IHC (p), FACS 宿主: 兔 Polyclonal RB02951 unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) antibodyMLL 适用: 人 IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (C-Term) antibodyMLL 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- ELISA: 1/10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Acute differentiated dendritic cell leukemia: a variant form of pediatric acute myeloid leukemia with MLL translocation." in: Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, Vol. 21, Issue 2, pp. 360-2, (2007) (PubMed).
: "Constitutional duplication 11q23 de novo involving the MLL gene." in: Genetic counseling (Geneva, Switzerland), Vol. 17, Issue 2, pp. 155-9, (2006) (PubMed).
: "MLL-SEPT6 fusion transcript with a novel sequence in an infant with acute myeloid leukemia." in: Cancer genetics and cytogenetics, Vol. 168, Issue 2, pp. 162-7, (2006) (PubMed).
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: "Acute differentiated dendritic cell leukemia: a variant form of pediatric acute myeloid leukemia with MLL translocation." in: Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, Vol. 21, Issue 2, pp. 360-2, (2007) (PubMed).
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- 抗原
- MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))
- 别名
- MLL (MLL 产品)
- 别名
- ALL-1 antibody, CXXC7 antibody, HRX antibody, HTRX1 antibody, MLL antibody, MLL/GAS7 antibody, MLL1A antibody, TET1-MLL antibody, TRX1 antibody, WDSTS antibody, 6430520K01 antibody, All1 antibody, Cxxc7 antibody, Mll antibody, Mll1 antibody, mKIAA4050 antibody, lysine methyltransferase 2A antibody, lysine (K)-specific methyltransferase 2A antibody, KMT2A antibody, Kmt2a antibody
- 背景
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Description: Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila). Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle,that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein, also designated MEN) functions as an RNA polymerase II elongation factor that increases the rateof transcription by suppressing transient pausing by RNA polymerase II. Also, ELL is thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, and has lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary.The gene encoding human ELL, which maps to chromosome 19p13.1, is one of several genes which undergo translocation with the MLL gene on chromo-some 11q23 in acute myeloid leukemia. MLL (myeloid/lymphoid leukemia,also designated ALL-1 and HRX) is a 430 kDa protein that regulates embryonal and hematopoietic development.
Aliases: MLL
- 基因ID
- 4297
- HGNC
- 4297
- UniProt
- Q03164
- 途径
- Warburg Effect
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