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MCM2 抗体

MCM2 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 1E7 unconjugated
产品编号 ABIN969281
发货至: 中国
  • 抗原 See all MCM2 抗体
    MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This MCM2 antibody is un-conjugated
    应用范围
    • 82
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    原理
    MCM2 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human MCM2 expressed in E. Coli.
    克隆位点
    1E7
    亚型
    IgG1
    Top Product
    Discover our top product MCM2 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Chuang, Teixeira, Wohlschlegel, Henze, Yates, Méndez, Reed: "Phosphorylation of Mcm2 by Cdc7 promotes pre-replication complex assembly during cell-cycle re-entry." in: Molecular cell, Vol. 35, Issue 2, pp. 206-16, (2009) (PubMed).

    Liaw, Boyd: "MCM 2 Expression in Basal Cell Carcinomas and Trichoepitheliomas." in: Journal of cutaneous pathology, Vol. 36, Issue 10, pp. 1121-2, (2009) (PubMed).

  • 抗原
    MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
    别名
    MCM2 (MCM2 产品)
    别名
    CG7538 antibody, DmMCM2 antibody, DmMcm2 antibody, DmeMCM2 antibody, Dmel\\CG7538 antibody, MCM2 antibody, MCM2-7 antibody, MCM2_DROME antibody, McM2 antibody, PCR3 antibody, dMCM2 antibody, l(3)rL074 antibody, XMcm2 antibody, bm28 antibody, ccnl1 antibody, cdc19 antibody, cdcl1 antibody, mitotin antibody, cb737 antibody, chunp6905 antibody, BM28 antibody, CCNL1 antibody, CDCL1 antibody, D3S3194 antibody, MITOTIN antibody, MCM7 antibody, AA959861 antibody, AW476101 antibody, Mcmd2 antibody, mKIAA0030 antibody, Minichromosome maintenance 2 antibody, minichromosome maintenance complex component 2 antibody, minichromosome maintenance complex component 2 L homeolog antibody, Mcm2 antibody, mcm2 antibody, MCM2 antibody, mcm2.L antibody
    背景

    Description: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.

    Aliases: BM28, CCNL1, CDCL1, cdc19, D3S3194, MITOTIN, KIAA0030, MGC10606

    分子量
    125kDa
    基因ID
    4171
    HGNC
    4171
    UniProt
    P49736
    途径
    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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