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MBP 抗体

MBP 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2H9 unconjugated
产品编号 ABIN969279
发货至: 中国
  • 抗原 See all MBP 抗体
    MBP (Myelin Basic Protein (MBP))
    适用
    • 111
    • 34
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    • 19
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    • 9
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    宿主
    • 79
    • 31
    • 10
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    • 1
    • 1
    小鼠
    克隆类型
    • 82
    • 42
    单克隆
    标记
    • 82
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    This MBP antibody is un-conjugated
    应用范围
    • 80
    • 44
    • 42
    • 14
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    • 11
    • 8
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    • 6
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    Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
    原理
    MBP Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human MBP expressed in E. Coli.
    克隆位点
    2H9
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Rajaraman, Brenner, Butler, Wang, Pfeiffer, Ruder, Linet, Yeager, Wang, Orr, Fine, Kwon, Thomas, Rothman, Inskip, Chanock: "Common variation in genes related to innate immunity and risk of adult glioma." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 5, pp. 1651-8, (2009) (PubMed).

    Hoos, Ahmed, Smith, Van Nostrand: "Myelin basic protein binds to and inhibits the fibrillar assembly of Abeta42 in vitro." in: Biochemistry, Vol. 48, Issue 22, pp. 4720-7, (2009) (PubMed).

  • 抗原
    MBP (Myelin Basic Protein (MBP))
    别名
    Myelin basic protein (MBP 产品)
    别名
    C76307 antibody, Hmbpr antibody, R75289 antibody, golli-mbp antibody, mld antibody, shi antibody, Mbps antibody, cb274 antibody, fj33b11 antibody, mbp antibody, wu:fj33b11 antibody, wu:fq15b02 antibody, zgc:136630 antibody, MGC115135 antibody, myelin basic protein antibody, myelin basic protein a antibody, myelin basic protein L homeolog antibody, MBP antibody, Mbp antibody, mbpa antibody, mbp antibody, mbp.L antibody
    背景

    Description: The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.

    Aliases: MGC99675

    分子量
    33kDa
    基因ID
    4155
    HGNC
    4155
    UniProt
    P02686
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