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MAP4K4 抗体 (AA 400-500)

MAP4K4 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4H9E7 unconjugated
产品编号 ABIN969274
发货至: 中国
  • 抗原 See all MAP4K4 抗体
    MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))
    抗原表位
    • 22
    • 10
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 400-500
    适用
    • 66
    • 19
    • 7
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 63
    • 3
    小鼠
    克隆类型
    • 62
    • 4
    单克隆
    标记
    • 34
    • 5
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAP4K4 antibody is un-conjugated
    应用范围
    • 35
    • 35
    • 15
    • 15
    • 10
    • 10
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    ELISA
    原理
    MAP4K4 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of MAP4K4 (aa400-500) expressed in E. Coli.
    克隆位点
    4H9E7
    亚型
    IgG1
    Top Product
    Discover our top product MAP4K4 Primary Antibody
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Bouzakri, Zierath: "MAP4K4 gene silencing in human skeletal muscle prevents tumor necrosis factor-alpha-induced insulin resistance." in: The Journal of biological chemistry, Vol. 282, Issue 11, pp. 7783-9, (2007) (PubMed).

    Poinat, De Arcangelis, Sookhareea, Zhu, Hedgecock, Labouesse, Georges-Labouesse: "A conserved interaction between beta1 integrin/PAT-3 and Nck-interacting kinase/MIG-15 that mediates commissural axon navigation in C. elegans." in: Current biology : CB, Vol. 12, Issue 8, pp. 622-31, (2002) (PubMed).

    Becker, Huynh-Do, Holland, Pawson, Daniel, Skolnik: "Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation." in: Molecular and cellular biology, Vol. 20, Issue 5, pp. 1537-45, (2000) (PubMed).

  • 抗原
    MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))
    别名
    MAP4K4 (MAP4K4 产品)
    别名
    FLH21957 antibody, HGK antibody, MEKKK4 antibody, NIK antibody, 9430080K19Rik antibody, AU043147 antibody, AU045934 antibody, AW046177 antibody, Nik antibody, mitogen-activated protein kinase kinase kinase kinase 4 antibody, MAP4K4 antibody, Map4k4 antibody
    背景

    Description: MAP4K4: mitogen-activated protein kinase kinase kinase kinase 4. The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified.

    Aliases: HGK, NIK

    基因ID
    9448
    HGNC
    9448
    UniProt
    O95819
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