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MAP3K2 抗体

MAP3K2 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 4B4 unconjugated
产品编号 ABIN969272
发货至: 中国
  • 抗原 See all MAP3K2 抗体
    MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))
    适用
    • 46
    • 29
    • 14
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 45
    • 2
    小鼠
    克隆类型
    • 38
    • 9
    单克隆
    标记
    • 20
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This MAP3K2 antibody is un-conjugated
    应用范围
    • 29
    • 20
    • 14
    • 4
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunocytochemistry (ICC)
    原理
    MAP3K2 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human MAP3K2 expressed in E. Coli.
    克隆位点
    4B4
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Kurada, Li, Mulherkar, Subramanian, Prasad, Prabhakar: "MADD, a splice variant of IG20, is indispensable for MAPK activation and protection against apoptosis upon tumor necrosis factor-alpha treatment." in: The Journal of biological chemistry, Vol. 284, Issue 20, pp. 13533-41, (2009) (PubMed).

    Cazares, Troyer, Mendrinos, Lance, Nyalwidhe, Beydoun, Clements, Drake, Semmes: "Imaging mass spectrometry of a specific fragment of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 2 discriminates cancer from uninvolved prostate tissue." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 17, pp. 5541-51, (2009) (PubMed).

  • 抗原
    MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))
    别名
    MAP3K2 (MAP3K2 产品)
    别名
    Mekk2 antibody, MEKK2 antibody, MEKK2B antibody, 9630061B06Rik antibody, AI585793 antibody, Mekk2b antibody, mitogen activated protein kinase kinase kinase 2 antibody, mitogen-activated protein kinase kinase kinase 2 antibody, Map3k2 antibody, MAP3K2 antibody
    背景

    Description: The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.

    Aliases: MEKK2, MEKK2B

    分子量
    70kDa
    基因ID
    10746
    HGNC
    10746
    UniProt
    Q9Y2U5
    途径
    MAPK Pathway
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