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- 抗原 See all MAP2K6 抗体
- MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MAP2K6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 原理
- MAP2K6 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human MAP2K6 expressed in E. Coli.
- 克隆位点
- 3H12B9
- 亚型
- IgG1
- Top Product
- Discover our top product MAP2K6 Primary Antibody
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- 应用备注
- ELISA: 1/10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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ASK1 and MAP2K6 as modifiers of age at onset in Huntington's disease." in: Journal of molecular medicine (Berlin, Germany), Vol. 86, Issue 4, pp. 485-90, (2008) (PubMed).
: "
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ASK1 and MAP2K6 as modifiers of age at onset in Huntington's disease." in: Journal of molecular medicine (Berlin, Germany), Vol. 86, Issue 4, pp. 485-90, (2008) (PubMed).
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- 抗原
- MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
- 别名
- MAP2K6 (MAP2K6 产品)
- 别名
- MAPKK6 antibody, MEK6 antibody, MKK6 antibody, PRKMK6 antibody, SAPKK-3 antibody, SAPKK3 antibody, Mkk6 antibody, Prkmk6 antibody, MKK3 antibody, map2k3 antibody, zMKK3 antibody, map2k6 antibody, mitogen-activated protein kinase kinase 6 antibody, mitogen-activated protein kinase kinase 6 L homeolog antibody, MAP2K6 antibody, Map2k6 antibody, map2k6 antibody, map2k6.L antibody
- 背景
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Description: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. Tissue specificity: Isoform 2 is only expressed in skeletal muscle. Isoform 1, on the other hand, is found in skeletal muscle, heart, and in lesser extent in liver or pancreas.
Aliases: MEK6, MKK6, MAPKK6, PRKMK6, SAPKK3, MAP2K6
- 分子量
- 38kDa
- 基因ID
- 5608
- HGNC
- 5608
- UniProt
- P52564
- 途径
- MAPK Pathway, TLR signaling, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
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