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LSD1 抗体

KDM1A 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 1B2E5 unconjugated
产品编号 ABIN969264
发货至: 中国
  • 抗原 See all LSD1 (KDM1A) 抗体
    LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))
    适用
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    宿主
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    小鼠
    克隆类型
    • 59
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    单克隆
    标记
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    This LSD1 antibody is un-conjugated
    应用范围
    • 68
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    原理
    LSD1/AOF2 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human LSD1 expressed in E. Coli.
    克隆位点
    1B2E5
    亚型
    IgG1
    Top Product
    Discover our top product KDM1A Primary Antibody
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shi, Matson, Lan, Iwase, Baba, Shi: "Regulation of LSD1 histone demethylase activity by its associated factors." in: Molecular cell, Vol. 19, Issue 6, pp. 857-64, (2005) (PubMed).

    Metzger, Wissmann, Yin, Müller, Schneider, Peters, Günther, Buettner, Schüle: "LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription." in: Nature, Vol. 437, Issue 7057, pp. 436-9, (2005) (PubMed).

  • 抗原
    LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))
    别名
    LSD1/AOF2 (KDM1A 产品)
    背景

    Description: The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95 kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.

    Aliases: KDM1, LSD1, AOF2

    分子量
    93kDa
    基因ID
    23028
    HGNC
    23028
    UniProt
    O60341
    途径
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, Warburg Effect
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