电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Lamin A/C 抗体

LMNA 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 4E7 unconjugated
产品编号 ABIN969260
发货至: 中国
  • 抗原 See all Lamin A/C (LMNA) 抗体
    Lamin A/C (LMNA)
    适用
    • 131
    • 73
    • 71
    • 27
    • 15
    • 13
    • 8
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 97
    • 44
    • 2
    • 1
    小鼠
    克隆类型
    • 96
    • 48
    单克隆
    标记
    • 113
    • 9
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    This Lamin A/C antibody is un-conjugated
    应用范围
    • 119
    • 54
    • 53
    • 48
    • 32
    • 31
    • 30
    • 20
    • 15
    • 7
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    原理
    LMNA Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human LMNA expressed in E. Coli.
    克隆位点
    4E7
    亚型
    IgG1
    Top Product
    Discover our top product LMNA Primary Antibody
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Carboni, Porcu, Mura, Cocco, Marrosu, Maioli, Solla, Tranquilli, Orrù, Marrosu: "Evolution of the phenotype in a family with an LMNA gene mutation presenting with isolated cardiac involvement." in: Muscle & nerve, Vol. 41, Issue 1, pp. 85-91, (2009) (PubMed).

  • 抗原
    Lamin A/C (LMNA)
    别名
    LMNA (LMNA 产品)
    背景

    Description: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

    Aliases: FPL, IDC, LFP, CDDC, EMD2, FPLD, HGPS, LDP1, LMN1, LMNC, PRO1, CDCD1, CMD1A, FPLD2, LMNL1, CMT2B1

    分子量
    74kDa
    基因ID
    4000
    HGNC
    4000
    UniProt
    P02545
    途径
    Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
You are here:
客服