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KRT15 抗体

KRT15 适用: 人 IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 6E7 unconjugated
产品编号 ABIN969250
发货至: 中国
  • 抗原 See all KRT15 抗体
    KRT15 (Keratin 15 (KRT15))
    适用
    • 93
    • 32
    • 26
    • 16
    • 2
    宿主
    • 67
    • 29
    • 2
    小鼠
    克隆类型
    • 58
    • 40
    单克隆
    标记
    • 45
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    This KRT15 antibody is un-conjugated
    应用范围
    • 51
    • 29
    • 20
    • 20
    • 16
    • 14
    • 14
    • 14
    • 14
    • 8
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    Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    原理
    KRT15 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of KRT15 expressed in E. Coli.
    克隆位点
    6E7
    亚型
    IgG2a
    Top Product
    Discover our top product KRT15 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Radoja, Stojadinovic, Waseem, Tomic-Canic, Milisavljevic, Teebor, Blumenberg: "Thyroid hormones and gamma interferon specifically increase K15 keratin gene transcription." in: Molecular and cellular biology, Vol. 24, Issue 8, pp. 3168-79, (2004) (PubMed).

    Werner, Munz: "Suppression of keratin 15 expression by transforming growth factor beta in vitro and by cutaneous injury in vivo." in: Experimental cell research, Vol. 254, Issue 1, pp. 80-90, (2000) (PubMed).

  • 抗原
    KRT15 (Keratin 15 (KRT15))
    别名
    KRT15 (KRT15 产品)
    别名
    xlk2 antibody, CK15 antibody, K15 antibody, K1CO antibody, AI528832 antibody, Krt1-15 antibody, Ka15 antibody, wu:fa91c06 antibody, wu:fa95d04 antibody, zgc:55334 antibody, keratin 15, type I L homeolog antibody, keratin 15, type I antibody, keratin 15 antibody, krt15.L antibody, krt15 antibody, KRT15 antibody, Krt15 antibody
    背景

    Description: The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 15 is a type I keratin without a defined type II partner. Keratin 15 is expressed primarily in the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. Expression of keratin 15 is downregulated in some hyperproliferating situations, such as psoriasis and hypertrophic scars. Because keratinocytes in psoriasis and hypertrophic scars are activated, it is suggested that keratin 15 expression is not compatible with keratinocyte activation and the keratin 15 gene is downregulated to maintain the activated phenotype.

    Aliases: K15, CK15, K1CO, KRT1

    分子量
    49kDa
    基因ID
    3866
    HGNC
    3866
    UniProt
    P19012
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