KLHL13 抗体
(2 references)-
- 抗原 See all KLHL13 抗体
- KLHL13 (Kelch-Like 13 (KLHL13))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This KLHL13 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 原理
- KLHL13 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human KLHL13 expressed in E. Coli.
- 克隆位点
- 8D1
- 亚型
- IgG1
-
anti-Kelch-Like 13 (KLHL13) (AA 1-260) antibody
KLHL13 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like 13 (KLHL13) (N-Term) antibodyKLHL13 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 马, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like 13 (KLHL13) (N-Term) antibodyKLHL13 适用: 人, 小鼠, Cow, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like 13 (KLHL13) (N-Term) antibodyKLHL13 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
: "Ubiquitin-dependent regulation of COPII coat size and function." in: Nature, Vol. 482, Issue 7386, pp. 495-500, (2012) (PubMed).
: "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions." in: Genome research, Vol. 14, Issue 9, pp. 1711-8, (2004) (PubMed).
-
: "Ubiquitin-dependent regulation of COPII coat size and function." in: Nature, Vol. 482, Issue 7386, pp. 495-500, (2012) (PubMed).
-
- 抗原
- KLHL13 (Kelch-Like 13 (KLHL13))
- 别名
- KLHL13 (KLHL13 产品)
- 别名
- 1200009K10Rik antibody, AI451128 antibody, Bklhd2 antibody, D130072F20Rik antibody, mKIAA1309 antibody, BKLHD2 antibody, Kelch-like protein 13 antibody, kelch-like 13 antibody, kelch like family member 13 antibody, kelch like family member 9 antibody, kelch-like family member 13 antibody, klh13 antibody, Klhl13 antibody, KLHL13 antibody, KLHL9 antibody
- 背景
-
Description: KLHL13 (kelch-like 13), also known as BKLHD2 (BTB and kelch domain-containing protein 2), is a 604 amino acid protein that contains six Kelch repeats and one BTB/POZ domain. Expressed predominantly in brain, KLHL13 is believed to play a role in protein ubiquitination and may function as a substrate- specific adapter of an E3 ubiquitin-protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, KLHL13 interacts with KLHL9 and CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Via its BTB and C-terminal Kelch (BACK) motif, KLHL13 is thought to play a role in spatially orientating substrates in the CUL-3 ligase.
Aliases: BKLHD2, FLJ10262, MGC74791, KLHL13
- 分子量
- 74kDa
- 基因ID
- 90293
- HGNC
- 90293
- UniProt
- Q9P2N7
-
