KDM3A 抗体
(4 references)-
- 抗原 See all KDM3A 抗体
- KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This KDM3A antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- 原理
- KDM3A Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human KDM3A expressed in E. Coli.
- 克隆位点
- 2E1
- 亚型
- IgG1
- Top Product
- Discover our top product KDM3A Primary Antibody
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anti-Lysine (K)-Specific Demethylase 3A (KDM3A) antibody
KDM3A 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3A (KDM3A) (AA 1-300) antibodyKDM3A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3A (KDM3A) (AA 311-445) antibodyKDM3A 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3G10C2 unconjugated
anti-Lysine (K)-Specific Demethylase 3A (KDM3A) (AA 1252-1301) antibodyKDM3A 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 豚鼠, 马, 兔, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3A (KDM3A) (AA 350-450) antibodyKDM3A 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3A (KDM3A) antibodyKDM3A 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 10E11 unconjugated
anti-Lysine (K)-Specific Demethylase 3A (KDM3A) (C-Term) antibodyKDM3A 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3A (KDM3A) (N-Term) antibodyKDM3A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3A (KDM3A) (AA 50-79), (N-Term) antibodyKDM3A 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB14307 unconjugated
anti-Lysine (K)-Specific Demethylase 3A (KDM3A) (N-Term) antibodyKDM3A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "KDM3A/Ets1/MCAM axis promotes growth and metastatic properties in Rhabdomyosarcoma." in: Genes & cancer, Vol. 11, Issue 1-2, pp. 53-65, (2020) (PubMed).
: "The histone demethylase KDM3A, and its downstream target MCAM, promote Ewing Sarcoma cell migration and metastasis." in: Oncogene, Vol. 36, Issue 29, pp. 4150-4160, (2017) (PubMed).
: "Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ..." in: Nature, Vol. 434, Issue 7034, pp. 724-31, (2005) (PubMed).
: "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 5, Issue 5, pp. 277-86, (1999) (PubMed).
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: "KDM3A/Ets1/MCAM axis promotes growth and metastatic properties in Rhabdomyosarcoma." in: Genes & cancer, Vol. 11, Issue 1-2, pp. 53-65, (2020) (PubMed).
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- 抗原
- KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))
- 别名
- KDM3A (KDM3A 产品)
- 别名
- JHDM2A antibody, JHMD2A antibody, JMJD1 antibody, JMJD1A antibody, TSGA antibody, tsga antibody, jmjd1 antibody, jhdm2a antibody, jhmd2a antibody, jmjd1a antibody, 1700105C21Rik antibody, C230043E16Rik antibody, JHDM2a antibody, Jmjd1 antibody, Jmjd1a antibody, KDM2A antibody, TGSA antibody, Tsga antibody, mKIAA0742 antibody, KDM3A antibody, kdm3a antibody, lysine demethylase 3A antibody, lysine (K)-specific demethylase 3A antibody, lysine-specific demethylase 3A antibody, lysine (K)-specific demethylase 3A S homeolog antibody, KDM3A antibody, kdm3a antibody, Kdm3a antibody, LOC100453519 antibody, kdm3a.S antibody
- 背景
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Description: This gene encodes a zinc finger protein that contains a jumonji domain and may play a role in hormone-dependent transcriptional activation. JMJD1A functions as a mono- and dimethylation-specific demethylase, binding iron and alpha-ketoglutarate as cofactors and demethylating Lysine 9 of Histone H3. This suggests that JMJD1A plays a central role in the histone code and participates in nuclear hormone receptor-based transcriptional regulation. In addition, JMJD1A plays an important role in the regulation of cell growth during development and in chromatin regulation. JMJD1A directly regulates the expression of TNP1 and Protamine 1 (proteins required for the proper packaging and condensation of sperm chromatin) and, therefore, plays an essential role in spermatogenesis.
Aliases: TSGA, JMJD1, JHDM2A, JHMD2A, JMJD1A, KIAA0742, DKFZp686A24246, DKFZp686P07111, KDM3A
- 分子量
- 147kDa
- 基因ID
- 55818
- HGNC
- 55818
- UniProt
- Q9Y4C1
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Warburg Effect
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