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- 抗原 See all ITK 抗体
- ITK (IL2-Inducible T-Cell Kinase (ITK))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ITK antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 原理
- ITK Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human ITK expressed in E. Coli.
- 克隆位点
- 5G6
- 亚型
- IgG1
- Top Product
- Discover our top product ITK Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation." in: The Journal of clinical investigation, Vol. 119, Issue 5, pp. 1350-8, (2009) (PubMed).
: "Tacrolimus differentially regulates the proliferation of conventional and regulatory CD4(+) T cells." in: Molecules and cells, Vol. 28, Issue 2, pp. 125-30, (2009) (PubMed).
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Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation." in: The Journal of clinical investigation, Vol. 119, Issue 5, pp. 1350-8, (2009) (PubMed).
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- 抗原
- ITK (IL2-Inducible T-Cell Kinase (ITK))
- 别名
- ITK (ITK 产品)
- 别名
- Emt antibody, Tcsk antibody, Tsk antibody, EMT antibody, LPFS1 antibody, LYK antibody, PSCTK2 antibody, IL2 inducible T cell kinase antibody, IL2 inducible T-cell kinase antibody, IL2-inducible T-cell kinase antibody, Itk antibody, ITK antibody
- 背景
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Description: This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.
Aliases: EMT, LYK, PSCTK2, MGC126257, MGC126258
- 分子量
- 72kDa
- 基因ID
- 3702
- HGNC
- 3702
- UniProt
- Q08881
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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