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- 抗原 See all ISL1 抗体
- ISL1 (ISL LIM Homeobox 1 (ISL1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ISL1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- 原理
- ISL1 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human ISL1 expressed in E. Coli.
- 克隆位点
- 1H9
- 亚型
- IgG1
- Top Product
- Discover our top product ISL1 Primary Antibody
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- 应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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The LIM-homeobox gene Islet-1 is required for the development of restricted forebrain cholinergic neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 28, Issue 13, pp. 3291-7, (2008) (PubMed).
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The LIM-homeobox gene Islet-1 is required for the development of restricted forebrain cholinergic neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 28, Issue 13, pp. 3291-7, (2008) (PubMed).
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- 抗原
- ISL1 (ISL LIM Homeobox 1 (ISL1))
- 别名
- ISL1 (ISL1 产品)
- 别名
- Xisl-1 antibody, Xislet-1 antibody, islet1 antibody, ISLET-1 antibody, ISLET1 antibody, Isl-1 antibody, islet-1 antibody, isl-1=homeobox antibody, Islet-1 antibody, ISL LIM homeobox 1 S homeolog antibody, ISL LIM homeobox 1 antibody, ISL1 transcription factor, LIM/homeodomain antibody, isl1.S antibody, ISL1 antibody, Isl1 antibody, isl1 antibody
- 背景
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Description: ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. Mutations in this gene have been associated with maturity-onset diabetes of the young.
Aliases: Isl-1, ISLET1
- 分子量
- 39kDa
- 基因ID
- 3670
- HGNC
- 3670
- UniProt
- P61371
- 途径
- Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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