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Hexokinase 1 抗体

HK1 适用: 人 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 7A7 unconjugated
产品编号 ABIN969194
发货至: 中国
  • 抗原 See all Hexokinase 1 (HK1) 抗体
    Hexokinase 1 (HK1)
    适用
    • 87
    • 46
    • 33
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 96
    • 11
    小鼠
    克隆类型
    • 87
    • 20
    单克隆
    标记
    • 58
    • 17
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This Hexokinase 1 antibody is un-conjugated
    应用范围
    • 86
    • 46
    • 37
    • 17
    • 16
    • 16
    • 11
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    原理
    HK1 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human HK1 expressed in E. Coli.
    克隆位点
    7A7
    亚型
    IgG1
    Top Product
    Discover our top product HK1 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Martins-de-Souza, Gattaz, Schmitt, Rewerts, Marangoni, Novello, Maccarrone, Turck, Dias-Neto: "Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis." in: Journal of neural transmission (Vienna, Austria : 1996), Vol. 116, Issue 3, pp. 275-89, (2009) (PubMed).

    Tsai: "Function of interdomain alpha-helix in human brain hexokinase: covalent linkage and catalytic regulation between N- and C-terminal halves." in: Journal of biomedical science, Vol. 14, Issue 2, pp. 195-202, (2007) (PubMed).

    Stelzl, Worm, Lalowski, Haenig, Brembeck, Goehler, Stroedicke, Zenkner, Schoenherr, Koeppen, Timm, Mintzlaff, Abraham, Bock, Kietzmann, Goedde, Toksöz, Droege, Krobitsch, Korn, Birchmeier, Lehrach et al.: "A human protein-protein interaction network: a resource for annotating the proteome. ..." in: Cell, Vol. 122, Issue 6, pp. 957-68, (2005) (PubMed).

  • 抗原
    Hexokinase 1 (HK1)
    别名
    HK1 (HK1 产品)
    背景

    Description: The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose- 6-phosphate. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids. Glucokinase lacks the N-terminal hydrophobic cluster. The hydrophobic cluster is thought to be necessary for membrane binding. This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases. HK I has been shown to be expressed in brain, kidney and heart tissues as well as in hepatoma cell lines.

    Aliases: HKI, HXK1, HK1-ta, HK1-tb, HK1-tc, HK1

    分子量
    102kDa
    基因ID
    3098
    HGNC
    3098
    UniProt
    P19367
    途径
    Carbohydrate Homeostasis, Warburg Effect
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