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HFE 抗体

HFE 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 3F1 unconjugated
产品编号 ABIN969192
发货至: 中国
  • 抗原 See all HFE 抗体
    HFE (Hemochromatosis (HFE))
    适用
    • 53
    • 8
    • 7
    • 5
    • 5
    • 2
    • 2
    • 1
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    • 1
    宿主
    • 49
    • 5
    小鼠
    克隆类型
    • 50
    • 4
    单克隆
    标记
    • 26
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This HFE antibody is un-conjugated
    应用范围
    • 42
    • 19
    • 13
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunocytochemistry (ICC)
    原理
    HFE Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human HFE expressed in E. Coli.
    克隆位点
    3F1
    亚型
    IgG1
    Top Product
    Discover our top product HFE Primary Antibody
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Hosgood, Menashe, He, Chanock, Lan: "PTEN identified as important risk factor of chronic obstructive pulmonary disease." in: Respiratory medicine, Vol. 103, Issue 12, pp. 1866-70, (2009) (PubMed).

    Valenti, Girelli, Valenti, Castagna, Como, Campostrini, Rametta, Dongiovanni, Messa, Fargion: "HFE mutations modulate the effect of iron on serum hepcidin-25 in chronic hemodialysis patients." in: Clinical journal of the American Society of Nephrology : CJASN, Vol. 4, Issue 8, pp. 1331-7, (2009) (PubMed).

  • 抗原
    HFE (Hemochromatosis (HFE))
    别名
    HFE (HFE 产品)
    别名
    HFE1 antibody, HH antibody, HLA-H antibody, MVCD7 antibody, TFQTL2 antibody, MR2 antibody, hemochromatosis antibody, HFE antibody, Hfe antibody
    背景

    Description: The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. 

    Aliases: HH; HFE1; HLA-H; MVCD7; TFQTL2; MGC103790; dJ221C16.10.1

    分子量
    40kDa
    基因ID
    3077
    HGNC
    3077
    UniProt
    Q30201
    途径
    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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