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GFI1 抗体

GFI1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5D7 unconjugated
产品编号 ABIN969174
发货至: 中国
  • 抗原 See all GFI1 抗体
    GFI1 (Growth Factor Independent 1 (GFI1))
    适用
    • 21
    • 16
    • 15
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    宿主
    • 17
    • 5
    小鼠
    克隆类型
    • 19
    • 3
    单克隆
    标记
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GFI1 antibody is un-conjugated
    应用范围
    • 14
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
    原理
    GFI1 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human GFI1 expressed in E. Coli.
    克隆位点
    5D7
    亚型
    IgG1
    Top Product
    Discover our top product GFI1 Primary Antibody
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Dwivedi, Anderson, Tilley, May, Morris: "Role of oncoprotein growth factor independent-1 (GFI1) in repression of 25-hydroxyvitamin D 1alpha-hydroxylase (CYP27B1): a comparative analysis in human prostate cancer and kidney cells." in: The Journal of steroid biochemistry and molecular biology, Vol. 103, Issue 3-5, pp. 742-6, (2007) (PubMed).

    Kimura, Wakamatsu, Suzuki, Ota, Nishikawa, Yamashita, Yamamoto, Sekine, Tsuritani, Wakaguri, Ishii, Sugiyama, Saito, Isono, Irie, Kushida, Yoneyama, Otsuka, Kanda, Yokoi, Kondo, Wagatsuma, Murakawa et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ..." in: Genome research, Vol. 16, Issue 1, pp. 55-65, (2006) (PubMed).

  • 抗原
    GFI1 (Growth Factor Independent 1 (GFI1))
    别名
    GFI1 (GFI1 产品)
    别名
    AW495828 antibody, Gfi-1 antibody, Pal-1 antibody, Pal1 antibody, GFI1 antibody, GFI-1 antibody, GFI1A antibody, SCN2 antibody, ZNF163 antibody, growth factor independent 1 antibody, growth factor independent 1 transcriptional repressor antibody, Gfi1 antibody, GFI1 antibody
    背景

    Description: This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.Expression of GFl1 ranges from the hematopoietic and lymphoid system, to sensory epithelia, lung and parts of the CNS.

    Aliases: SCN2, GFI-1, ZNF163, FLJ94509, GFI1

    分子量
    45kDa
    基因ID
    2672
    HGNC
    2672
    UniProt
    Q99684
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