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GATA4 抗体

GATA4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6H10 unconjugated
产品编号 ABIN969169
发货至: 中国
  • 抗原 See all GATA4 抗体
    GATA4 (GATA Binding Protein 4 (GATA4))
    适用
    • 89
    • 65
    • 63
    • 6
    • 4
    • 2
    • 1
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    宿主
    • 81
    • 8
    • 1
    小鼠
    克隆类型
    • 73
    • 17
    单克隆
    标记
    • 55
    • 4
    • 3
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    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This GATA4 antibody is un-conjugated
    应用范围
    • 65
    • 30
    • 22
    • 19
    • 13
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    • 12
    • 6
    • 5
    • 2
    • 1
    • 1
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    Western Blotting (WB), ELISA
    原理
    GATA4 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human GATA4 expressed in E. Coli.
    克隆位点
    6H10
    亚型
    IgG2b
    Top Product
    Discover our top product GATA4 Primary Antibody
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Rajagopal, Ma, Obler, Shen, Manichaikul, Tomita-Mitchell, Boardman, Briggs, Garg, Srivastava, Goldmuntz, Broman, Benson, Smoot, Pu: "Spectrum of heart disease associated with murine and human GATA4 mutation." in: Journal of molecular and cellular cardiology, Vol. 43, Issue 6, pp. 677-85, (2007) (PubMed).

    Belaguli, Sepulveda, Nigam, Charron, Nemer, Schwartz: "Cardiac tissue enriched factors serum response factor and GATA-4 are mutual coregulators." in: Molecular and cellular biology, Vol. 20, Issue 20, pp. 7550-8, (2000) (PubMed).

  • 抗原
    GATA4 (GATA Binding Protein 4 (GATA4))
    别名
    GATA4 (GATA4 产品)
    别名
    gata-4 antibody, xgata4 antibody, xGATA-4 antibody, MGC81427 antibody, GATA4 antibody, GATA-4 antibody, Gata4 antibody, gata4 antibody, ASD2 antibody, VSD1 antibody, Gata-4 antibody, gata antibody, GATA binding protein 4 antibody, GATA binding protein 4 L homeolog antibody, glutamyl-tRNA(Gln) amidotransferase subunit A antibody, gata4 transcription factor antibody, GATA binding protein 4 S homeolog antibody, GATA4 antibody, gata4.L antibody, gata4 antibody, gatA4 antibody, Gata4 antibody, gata4.S antibody
    背景

    Description: GATA binding protein 4, also known as GATA4, it is a 46 kDa member of the GATA family of zinc-finger transcription factors. Members of this family is involved in the development of cardiac hypertrophy and remodeling, and plays a critical role in regulating basal and agonist or stress induced gene expression in cardiac and smooth muscle cell types. These factors recognize the GATA motif which is present in the promoters of many genes. GATA4 contains a conserved MAPK phosphorylation site at serine 105 within the transcriptional activation domain. Serine 105 of GATA4 is phosphorylated in response to agonist stimulation through MEK 1 ERK1 / 2, and weakly through JNK or p38 MAPKs. GATA4 is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in this gene have been associated with cardiac septal defects.

    Aliases: MGC126629

    分子量
    46kDa
    基因ID
    2626
    HGNC
    2626
    UniProt
    P43694
    途径
    Peptide Hormone Metabolism, Carbohydrate Homeostasis
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