GATA3 抗体 (AA 175-388)
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- 抗原 See all GATA3 抗体
- GATA3 (GATA Binding Protein 3 (GATA3))
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抗原表位
- AA 175-388
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This GATA3 antibody is un-conjugated
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应用范围
- ELISA
- 原理
- GATA3 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of GATA3 (aa175-388) expressed in E. Coli.
- 克隆位点
- 1A10D1
- 亚型
- IgG1
- Top Product
- Discover our top product GATA3 Primary Antibody
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- 应用备注
- ELISA: 1/10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Aberrant gata-3 expression in human pancreatic cancer." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 54, Issue 2, pp. 161-9, (2006) (PubMed).
: "Regulation of GATA-3, c-maf and T-bet mRNA expression in bronchoalveolar lavage cells and bronchial biopsies after segmental allergen challenge." in: International archives of allergy and immunology, Vol. 139, Issue 4, pp. 306-16, (2006) (PubMed).
: "Identification of GATA3 as a breast cancer prognostic marker by global gene expression meta-analysis." in: Cancer research, Vol. 65, Issue 24, pp. 11259-64, (2005) (PubMed).
: "Development of a new biotic index to assess freshwater pollution." in: Environmental pollution (Barking, Essex : 1987), Vol. 139, Issue 2, pp. 306-17, (2005) (PubMed).
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Aberrant gata-3 expression in human pancreatic cancer." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 54, Issue 2, pp. 161-9, (2006) (PubMed).
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- 抗原
- GATA3 (GATA Binding Protein 3 (GATA3))
- 别名
- GATA3 (GATA3 产品)
- 背景
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Description: GATA3: GATA binding protein 3. The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins. Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes. GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain. GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells, macrophages, or HeLa cell lines. GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers. Labastie et al. (1994) cloned the human gene and the 5-prime end of the mouse gene. The human gene comprises 6 exons distributed over 17 kb of DNA. Its 2 zinc fingers are encoded by 2 separate exons highly conserved with those of GATA1,but no other structural homologies between the 2 genes could be found.
Aliases: HDR
- 基因ID
- 2625
- HGNC
- 2625
- UniProt
- P23771
- 途径
- Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
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