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FOXP3 抗体

FOXP3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C7 unconjugated
产品编号 ABIN969156
发货至: 中国
  • 抗原 See all FOXP3 抗体
    FOXP3 (Forkhead Box P3 (FOXP3))
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    小鼠
    克隆类型
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    单克隆
    标记
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    This FOXP3 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human FOXP3 expressed in E. coli.
    克隆位点
    4C7
    亚型
    IgG1
    Top Product
    Discover our top product FOXP3 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Yuan, Chen, Li, Dong, Xue, Wang, Zhang, Wang, Zhang, Ge, Shen, Xu: "Elevated expression of Foxp3 in tumor-infiltrating Treg cells suppresses T-cell proliferation and contributes to gastric cancer progression in a COX-2-dependent manner." in: Clinical immunology (Orlando, Fla.), Vol. 134, Issue 3, pp. 277-88, (2010) (PubMed).

    Sarigul, Yazisiz, Bassorgun, Ulker, Avci, Erbasan, Gelen, Gorczynski, Terzioglu: "The numbers of Foxp3 + Treg cells are positively correlated with higher grade of infiltration at the salivary glands in primary Sjogren's syndrome." in: Lupus, Vol. 19, Issue 2, pp. 138-45, (2010) (PubMed).

  • 抗原
    FOXP3 (Forkhead Box P3 (FOXP3))
    别名
    FOXP3 (FOXP3 产品)
    别名
    foxp3 antibody, FOXP3 antibody, AIID antibody, DIETER antibody, IPEX antibody, PIDX antibody, XPID antibody, JM2 antibody, scurfin antibody, sf antibody, RGD1562112 antibody, forkhead box P3 antibody, forkhead box P3a antibody, forkhead box P3 L homeolog antibody, FOXP3 antibody, foxp3a antibody, foxp3 antibody, foxp3.L antibody, Foxp3 antibody
    背景

    Description: FOXP3 (a 431 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, at low level in CD4 positive/CD25 negative cells, and is absent in CD4 negative/CD8 positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.

    Aliases: JM2, AIID, IPEX, PIDX, XPID, DIETER, MGC141961, MGC141963, FOXP3

    分子量
    47.2 kDa
    基因ID
    50943
    HGNC
    50943
    途径
    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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