FMR1 抗体
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- 抗原 See all FMR1 抗体
- FMR1 (Fragile X Mental Retardation 1 (FMR1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FMR1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
- 原理
- FMR1 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human FMR1 expressed in E. Coli.
- 克隆位点
- 4G9
- 亚型
- IgG1
- Top Product
- Discover our top product FMR1 Primary Antibody
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- 应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- FMR1 (Fragile X Mental Retardation 1 (FMR1))
- 别名
- FMR1 (FMR1 产品)
- 背景
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Description: FMR1, also known as POF, FMRP, FRAXA. Entrez Protein: NP_002015. It is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs.
Aliases: POF; FMRP; POF1; FRAXA
- 分子量
- 71kDa
- 基因ID
- 2332
- HGNC
- 2332
- UniProt
- Q06787
- 途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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