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FER 抗体

FER 适用: 人, 小鼠 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 5D2C4 unconjugated
产品编号 ABIN969133
发货至: 中国
  • 抗原 See all FER 抗体
    FER (FER Tyrosine Kinase (FER))
    适用
    • 74
    • 69
    • 15
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 93
    • 9
    小鼠
    克隆类型
    • 93
    • 9
    单克隆
    标记
    • 42
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This FER antibody is un-conjugated
    应用范围
    • 80
    • 36
    • 26
    • 26
    • 14
    • 12
    • 12
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human FER expressed in E. coli.
    克隆位点
    5D2C4
    亚型
    IgG1
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Li, Cheng, Ling: "Isolation and characterization of Fe(III)-chelate reductase gene LeFRO1 in tomato." in: Plant molecular biology, Vol. 54, Issue 1, pp. 125-36, (2004) (PubMed).

    Girault, Greengard: "The neurobiology of dopamine signaling." in: Archives of neurology, Vol. 61, Issue 5, pp. 641-4, (2004) (PubMed).

    Fan, Di Ciano-Oliveira, Weed, Craig, Greer, Rotstein, Kapus: "Actin depolymerization-induced tyrosine phosphorylation of cortactin: the role of Fer kinase." in: The Biochemical journal, Vol. 380, Issue Pt 2, pp. 581-91, (2004) (PubMed).

  • 抗原
    FER (FER Tyrosine Kinase (FER))
    别名
    FER (FER 产品)
    别名
    FerT antibody, PPP1R74 antibody, TYK3 antibody, Fer antibody, Flk antibody, Flk_retired antibody, AV082135 antibody, C330004K01Rik antibody, Fert antibody, FER tyrosine kinase antibody, fer (fms/fps related) protein kinase antibody, FER antibody, Fer antibody
    背景

    Description: FER (fer tyrosine kinase) is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases, which shares a functional domain and is involved in signaling pathways through receptor tyrosine kinases (RTK) and cytokine receptors. The Fes /Fps family is distinct from c-Src, c-Abl and related nRTKs and was originally distinguished as a homolog to retroviral oncoproteins. In vivo, Fer kinase assembles into homotrimers via conserved coiled-coil domains. The N-terminal coiled-coil domains of Fer can autophosphorylate in trans, thereby regulating their cellular function through differential phosphorylation states. Growth factor exposure can induce tyrosine phosphorylation of Fer and recruitment of Fer to RTK complexes containing p85. It is expressed predominantly in mature hematopoietic cells of the granulocytic and monocytic lineage, and has been shown to be expressed in vascular endothelial cells. Fer is implicated in insulin signaling, cell-cell signaling, human prostatic proliferative diseases, and is involved in the regulation of G1 progression.

    Aliases: TYK3, FER

    分子量
    95 kDa
    基因ID
    2241
    HGNC
    2241
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