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FAK 抗体

PTK2 适用: 人 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 10H7 unconjugated
产品编号 ABIN969130
发货至: 中国
  • 抗原 See all FAK (PTK2) 抗体
    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
    适用
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    宿主
    • 363
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    小鼠
    克隆类型
    • 359
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    单克隆
    标记
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    This FAK antibody is un-conjugated
    应用范围
    • 301
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    原理
    FAK Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human FAK expressed in E. Coli.
    克隆位点
    10H7
    亚型
    IgG1
    Top Product
    Discover our top product PTK2 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Toutant, Costa, Studler, Kadaré, Carnaud, Girault: "Alternative splicing controls the mechanisms of FAK autophosphorylation." in: Molecular and cellular biology, Vol. 22, Issue 22, pp. 7731-43, (2002) (PubMed).

    Huang, Cheung, Parsons, Bryer-Ash: "Focal adhesion kinase (FAK) regulates insulin-stimulated glycogen synthesis in hepatocytes." in: The Journal of biological chemistry, Vol. 277, Issue 20, pp. 18151-60, (2002) (PubMed).

  • 抗原
    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
    别名
    FAK (PTK2 产品)
    别名
    FADK antibody, FAK antibody, FAK1 antibody, FRNK antibody, PPP1R71 antibody, p125FAK antibody, pp125FAK antibody, PTK2 antibody, Fadk antibody, mKIAA4203 antibody, fak antibody, fak1a antibody, ptk2 antibody, ptk2a antibody, wu:fa18c04 antibody, zgc:66114 antibody, CG10023 antibody, CT28129 antibody, DFAK antibody, DFak antibody, DFak56 antibody, Dfak antibody, Dfak56 antibody, DmFAK antibody, Dmel\\CG10023 antibody, Fak56 antibody, Fak56D antibody, fak56 antibody, protein tyrosine kinase 2 antibody, protein tyrosine kinase 2 L homeolog antibody, PTK2 protein tyrosine kinase 2 antibody, protein tyrosine kinase 2ab antibody, Focal adhesion kinase antibody, PTK2 antibody, ptk2.L antibody, Ptk2 antibody, ptk2ab antibody, Fak antibody
    背景

    Description: This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined. Tissue specificity: Expressed in all organs tested, in lymphoid cell lines, but most abundantly in brain.RD: Focal adhesion kinase 1 (FAK) is a ubiquitously expressed non-receptor protein tyrosine kinase that is concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This cellular localization is directed by a

    Aliases: FAK, FADK, FAK1, FRNK, pp125FAK, PTK2

    分子量
    119kDa
    基因ID
    5747
    HGNC
    5747
    UniProt
    Q05397
    途径
    Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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