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ETV4 抗体 (AA 50-109)

ETV4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A2G3 unconjugated
产品编号 ABIN969121
发货至: 中国
  • 抗原 See all ETV4 抗体
    ETV4 (Ets Variant 4 (ETV4))
    抗原表位
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 50-109
    适用
    • 27
    • 22
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 25
    • 1
    • 1
    小鼠
    克隆类型
    • 26
    • 1
    单克隆
    标记
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ETV4 antibody is un-conjugated
    应用范围
    • 17
    • 10
    • 8
    • 6
    • 5
    • 4
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human ETV4 (aa50-109) expressed in E. coli.
    克隆位点
    1A2G3
    亚型
    IgG1
    Top Product
    Discover our top product ETV4 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Yu, Xia, Wang, Wang, Pan, Kwong, Hortobagyi, Hung: "Antitumor activity of an Ets protein, PEA3, in breast cancer cell lines MDA-MB-361DYT2 and BT474M1." in: Molecular carcinogenesis, Vol. 45, Issue 9, pp. 667-75, (2006) (PubMed).

    Matsui, Sugimori, Motomura, Ejiri, Tsukada, Kitajima: "PEA3 cooperates with c-Jun in regulation of HER2/neu transcription." in: Oncology reports, Vol. 16, Issue 1, pp. 153-8, (2006) (PubMed).

    Zhu, Jiang, Shen, Wang, Zong, Li, Yang, Niu, Liu, Chen, Hu, Gu: "Elevated beta1,4-galactosyltransferase I in highly metastatic human lung cancer cells. Identification of E1AF as important transcription activator." in: The Journal of biological chemistry, Vol. 280, Issue 13, pp. 12503-16, (2005) (PubMed).

  • 抗原
    ETV4 (Ets Variant 4 (ETV4))
    别名
    ETV4 (ETV4 产品)
    别名
    E1A-F antibody, E1AF antibody, PEA3 antibody, PEAS3 antibody, Pea3 antibody, AW414408 antibody, Pea-3 antibody, pea3 antibody, ETS variant 4 antibody, ets variant 4 antibody, ETV4 antibody, Etv4 antibody, etv4 antibody
    背景

    Description: ETV4: ets variant gene 4 (E1A enhancer binding protein, E1AF), also known as PEA3. Several members of the Ets gene family are known to encode sequencespecific DNA binding proteins. These include mouse PU.1, mouse and human Ets-1, Drosophila E74, chicken and human Ets-2 and rat GABP-α. Each of these proteins recognizes similar motifs in DNA that share a centrally located 5'-GGAA-3' element. For instance, PEA3 binds the motif 5'-AGGAAG-3' (the PEA-3 motif), but does not bind to the sequence 5'-AGGAAC-3', recognized by PU.1, although PU.1 binds equally well to both sequences. It appears that all of the Ets proteins recognize the same central core sequence but that each protein interacts with unique sequences that flank this core. PEA3 is expressed at readily detectable levels in cells of epithelial and fibroblastic origin but is not expressed in hematopoietic cells. This is in contrast to other members of the Ets gene family, such as Ets-1, Ets-2 and Fli-1, each of which is expressed primarily in cells of hematopoietic origin.

    Aliases: HGK, NIK, PEA3

    分子量
    54 kDa
    基因ID
    2118
    HGNC
    2118
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