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MAPK6 抗体

MAPK6 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4E8 unconjugated
产品编号 ABIN969115
发货至: 中国
  • 抗原 See all MAPK6 抗体
    MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))
    适用
    • 47
    • 38
    • 19
    • 5
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    宿主
    • 54
    • 5
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    • 1
    小鼠
    克隆类型
    • 59
    • 4
    单克隆
    标记
    • 38
    • 5
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    This MAPK6 antibody is un-conjugated
    应用范围
    • 49
    • 33
    • 19
    • 14
    • 13
    • 11
    • 9
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    • 3
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    • 1
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    ELISA, Flow Cytometry (FACS)
    原理
    ERK3 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human ERK3 expressed in E. Coli.
    克隆位点
    4E8
    亚型
    IgG1
    Top Product
    Discover our top product MAPK6 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Klinger, Turgeon, Lévesque, Wood, Aagaard-Tillery, Meloche: "Loss of Erk3 function in mice leads to intrauterine growth restriction, pulmonary immaturity, and neonatal lethality." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 39, pp. 16710-5, (2009) (PubMed).

    Déléris, Rousseau, Coulombe, Rodier, Tanguay, Meloche: "Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5." in: Journal of cellular physiology, Vol. 217, Issue 3, pp. 778-88, (2008) (PubMed).

  • 抗原
    MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))
    别名
    ERK3 (MAPK6 产品)
    背景

    Description: The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. (provided by RefSeq) Tissue specificity: Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts

    Aliases: ERK3, PRKM6, p97MAPK, HsT17250, DKFZp686F03189, MAPK6

    分子量
    105kDa
    基因ID
    5597
    HGNC
    5597
    UniProt
    Q16659
    途径
    MAPK Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C
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