EIF4E 抗体
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- 抗原 See all EIF4E 抗体
- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This EIF4E antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 原理
- EIF4E Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human EIF4E expressed in E. Coli.
- 克隆位点
- 5D11
- 亚型
- IgG1
- Top Product
- Discover our top product EIF4E Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Kinetic mechanism for assembly of the m7GpppG.eIF4E.eIF4G complex." in: The Journal of biological chemistry, Vol. 283, Issue 37, pp. 25227-37, (2008) (PubMed).
: "A prospective trial on initiation factor 4E (eIF4E) overexpression and cancer recurrence in node-negative breast cancer." in: Annals of surgical oncology, Vol. 15, Issue 11, pp. 3207-15, (2008) (PubMed).
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Kinetic mechanism for assembly of the m7GpppG.eIF4E.eIF4G complex." in: The Journal of biological chemistry, Vol. 283, Issue 37, pp. 25227-37, (2008) (PubMed).
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- 抗原
- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
- 别名
- EIF4E (EIF4E 产品)
- 别名
- AUTS19 antibody, CBP antibody, EIF4E1 antibody, EIF4EL1 antibody, EIF4F antibody, eif4e-1 antibody, zgc:86680 antibody, EG668879 antibody, Eif4e-ps antibody, If4e antibody, eIF-4E antibody, 0260/09 antibody, 0587/11 antibody, 0589/11 antibody, 0919/12 antibody, 1004/13 antibody, 2 antibody, 7238 antibody, CG4035 antibody, CT13384 antibody, CT39424 antibody, CT39426 antibody, D-eIF4E antibody, Dmel\\CG4035 antibody, Eif4E antibody, Eif4e antibody, IF4E antibody, dEif4e antibody, deIF-4E antibody, deIF4E antibody, eIF 4E antibody, eIF-4E1 antibody, eIF-4E2 antibody, eIF-4EII antibody, eIF-4e antibody, eIF4E antibody, eIF4E-1 antibody, eIF4E-1/2 antibody, eIF4E-2 antibody, eIF4E1 antibody, eIF4EI antibody, eIF4e antibody, eif-4E antibody, eif-4e antibody, eif4e antibody, l(3)07238 antibody, l(3)67Af antibody, l(3)S025007 antibody, l(3)S026009 antibody, l(3)S058711 antibody, l(3)S091912 antibody, cbp antibody, eif4f antibody, eif4e1 antibody, eif4el1 antibody, EIF-4E antibody, zgc:101581 antibody, eukaryotic translation initiation factor 4E antibody, eukaryotic translation initiation factor 4ea antibody, Eukaryotic initiation factor 4E antibody, eucaryotic initiation factor 6 antibody, eukaryotic translation initiation factor 4E L homeolog antibody, eukaryotic translation initiation factor 4E family member 1B S homeolog antibody, translation initiation factor eIF4E antibody, eukaryotic translation initiation factor 4eb antibody, EIF4E antibody, eif4ea antibody, Eif4e antibody, eIF-4E antibody, eif6 antibody, eif4e antibody, eif4e.L antibody, eif4e1b.S antibody, LOC100533326 antibody, eif4eb antibody
- 背景
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Description: eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types. Several kinases are currently being investigated as potential regulators of eIF4E including PKC and/or the MAP kinase activated Mnk.
Aliases: CBP, EIF4F, EIF4E1, EIF4EL1, MGC111573, EIF4E
- 分子量
- 25kDa
- 基因ID
- 1977
- HGNC
- 1977
- UniProt
- P06730
- 途径
- BCR Signaling
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