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- 抗原 See all DLK1 抗体
- DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This DLK1 antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 原理
- DLK1 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human DLK1 expressed in E. Coli.
- 克隆位点
- 3A10
- 亚型
- IgG1
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Induction of Dlk1 by PTTG1 inhibits adipocyte differentiation and correlates with malignant transformation." in: Molecular biology of the cell, Vol. 20, Issue 14, pp. 3353-62, (2009) (PubMed).
: "Methylation analysis of the imprinted DLK1-GTL2 domain supports the random parental origin of the IGH-involving del(14q) in B-cell malignancies." in: Epigenetics, Vol. 4, Issue 7, pp. 469-75, (2009) (PubMed).
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Induction of Dlk1 by PTTG1 inhibits adipocyte differentiation and correlates with malignant transformation." in: Molecular biology of the cell, Vol. 20, Issue 14, pp. 3353-62, (2009) (PubMed).
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- 抗原
- DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
- 别名
- DLK1 (DLK1 产品)
- 别名
- DELTA1 antibody, DL1 antibody, Delta antibody, DLK antibody, DLK-1 antibody, Delta1 antibody, FA1 antibody, PREF1 antibody, Pref-1 antibody, ZOG antibody, pG2 antibody, AW742678 antibody, DlkI antibody, Ly107 antibody, Peg9 antibody, SCP1 antibody, pref-1 antibody, Zog antibody, delta like canonical Notch ligand 1 antibody, delta like non-canonical Notch ligand 1 antibody, delta-like 1 homolog (Drosophila) antibody, delta-like 1 (Drosophila) antibody, DLL1 antibody, DLK1 antibody, Dll1 antibody, Dlk1 antibody
- 背景
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Description: This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes, it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance, this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.
Aliases: DLK, FA1, ZOG, pG2, PREF1, Pref-1
- 分子量
- 41kDa
- 基因ID
- 8788
- HGNC
- 8788
- UniProt
- P80370
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