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DLK1 抗体

DLK1 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3A10 unconjugated
产品编号 ABIN969086
发货至: 中国
  • 抗原 See all DLK1 抗体
    DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
    适用
    • 57
    • 39
    • 30
    • 17
    • 4
    • 2
    • 1
    • 1
    宿主
    • 58
    • 7
    • 6
    小鼠
    克隆类型
    • 61
    • 10
    单克隆
    标记
    • 36
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This DLK1 antibody is un-conjugated
    应用范围
    • 58
    • 30
    • 23
    • 14
    • 13
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    原理
    DLK1 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human DLK1 expressed in E. Coli.
    克隆位点
    3A10
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Espina, Méndez-Vidal, Moreno-Mateos, Sáez, Romero-Franco, Japón, Pintor-Toro: "Induction of Dlk1 by PTTG1 inhibits adipocyte differentiation and correlates with malignant transformation." in: Molecular biology of the cell, Vol. 20, Issue 14, pp. 3353-62, (2009) (PubMed).

    Katrincsakova, Takeda, Urbankova, Michaux, Jarosova, Vandenberghe, Georges, Charlier, Wlodarska: "Methylation analysis of the imprinted DLK1-GTL2 domain supports the random parental origin of the IGH-involving del(14q) in B-cell malignancies." in: Epigenetics, Vol. 4, Issue 7, pp. 469-75, (2009) (PubMed).

  • 抗原
    DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
    别名
    DLK1 (DLK1 产品)
    别名
    DELTA1 antibody, DL1 antibody, Delta antibody, DLK antibody, DLK-1 antibody, Delta1 antibody, FA1 antibody, PREF1 antibody, Pref-1 antibody, ZOG antibody, pG2 antibody, AW742678 antibody, DlkI antibody, Ly107 antibody, Peg9 antibody, SCP1 antibody, pref-1 antibody, Zog antibody, delta like canonical Notch ligand 1 antibody, delta like non-canonical Notch ligand 1 antibody, delta-like 1 homolog (Drosophila) antibody, delta-like 1 (Drosophila) antibody, DLL1 antibody, DLK1 antibody, Dll1 antibody, Dlk1 antibody
    背景

    Description: This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes, it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance, this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.

    Aliases: DLK, FA1, ZOG, pG2, PREF1, Pref-1

    分子量
    41kDa
    基因ID
    8788
    HGNC
    8788
    UniProt
    P80370
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