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CRTC3 抗体

CRTC3 适用: 人 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 5G9 unconjugated
产品编号 ABIN969068
发货至: 中国
  • 抗原 See all CRTC3 抗体
    CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))
    适用
    • 37
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    宿主
    • 34
    • 3
    小鼠
    克隆类型
    • 34
    • 3
    单克隆
    标记
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    This CRTC3 antibody is un-conjugated
    应用范围
    • 24
    • 13
    • 13
    • 10
    • 7
    • 6
    • 3
    • 3
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    • 2
    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
    原理
    CRTC3 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human CRTC3 expressed in E. Coli.
    克隆位点
    5G9
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Nakayama, Miyabe, Okabe, Sakuma, Ijichi, Hasegawa, Nagatsuka, Shimozato, Inagaki: "Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 22, Issue 12, pp. 1575-81, (2009) (PubMed).

    Fehr, Röser, Heidorn, Hallas, Löning, Bullerdiek: "A new type of MAML2 fusion in mucoepidermoid carcinoma." in: Genes, chromosomes & cancer, Vol. 47, Issue 3, pp. 203-6, (2008) (PubMed).

  • 抗原
    CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))
    别名
    CRTC3 (CRTC3 产品)
    别名
    torc3 antibody, MGC146372 antibody, 2610312F20Rik antibody, 6332415K15Rik antibody, AI429792 antibody, BC011210 antibody, TORC3 antibody, RGD1309666 antibody, TORC-3 antibody, CREB regulated transcription coactivator 3 antibody, CREB regulated transcription coactivator 3 L homeolog antibody, CRTC3 antibody, crtc3 antibody, Crtc3 antibody, crtc3.L antibody
    背景

    Description: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) .Tissue specificity: Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach.

    Aliases: TORC3, FLJ21868, CRTC3

    分子量
    68kDa
    基因ID
    64784
    HGNC
    64784
    UniProt
    Q6UUV7
    途径
    SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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