Crk 抗体
-
- 抗原 See all Crk (CRK) 抗体
- Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This Crk antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human CRK expressed in E. coli.
- 克隆位点
- 3G11C1
- 亚型
- IgG2b
-
-
- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
-
-
Adaptor protein Crk induces Src-dependent activation of p38 MAPK in regulation of synovial sarcoma cell proliferation." in: Molecular cancer research : MCR, Vol. 7, Issue 9, pp. 1582-92, (2009) (PubMed).
: "[Biological roles of signaling adaptor protein CRK]." in: Seikagaku. The Journal of Japanese Biochemical Society, Vol. 81, Issue 5, pp. 361-76, (2009) (PubMed).
: "
-
Adaptor protein Crk induces Src-dependent activation of p38 MAPK in regulation of synovial sarcoma cell proliferation." in: Molecular cancer research : MCR, Vol. 7, Issue 9, pp. 1582-92, (2009) (PubMed).
-
- 抗原
- Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))
- 别名
- CRK (CRK 产品)
- 别名
- CG1587 antibody, CRK antibody, D-CRK antibody, D-Crk antibody, DCrk antibody, Dcrk antibody, Dmel\\CG1587 antibody, crk antibody, dCRK antibody, dCrk antibody, fb34h10 antibody, fc05a01 antibody, fi19g05 antibody, wu:fb34h10 antibody, wu:fc05a01 antibody, wu:fc54a04 antibody, wu:fi19g05 antibody, zgc:100936 antibody, CRKII antibody, p38 antibody, Crko antibody, crk2 antibody, crkII antibody, v-crk antibody, P38C-CRK antibody, Crk-I antibody, Crk-II antibody, Crk-III antibody, Crk3 antibody, CrkIII antibody, c-Crk antibody, Crk oncogene antibody, v-crk avian sarcoma virus CT10 oncogene homolog antibody, CRK proto-oncogene, adaptor protein antibody, v-crk avian sarcoma virus CT10 oncogene homolog L homeolog antibody, v-crk sarcoma virus CT10 oncogene homolog antibody, Crk antibody, crk antibody, CRK antibody, crk.L antibody
- 背景
-
Description: This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
Aliases: CRKII
- 分子量
- 42 kDa
- 基因ID
- 1398
- HGNC
- 1398
- 途径
- Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor
-