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Chitotriosidase 1 抗体 (AA 22-137)

CHIT1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1D9G2 unconjugated
产品编号 ABIN969053
发货至: 中国
  • 抗原 See all Chitotriosidase 1 (CHIT1) 抗体
    Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
    抗原表位
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-137
    适用
    • 31
    • 5
    • 2
    宿主
    • 24
    • 8
    • 1
    小鼠
    克隆类型
    • 27
    • 6
    单克隆
    标记
    • 22
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Chitotriosidase 1 antibody is un-conjugated
    应用范围
    • 20
    • 11
    • 9
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA
    原理
    CHIT1 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of CHIT1 (aa22-137) expressed in E. Coli.
    克隆位点
    1D9G2
    亚型
    IgG1
    Top Product
    Discover our top product CHIT1 Primary Antibody
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Wajner, Michelin, Burin, Pires, Pereira, Giugliani, Coelho et al.: "Comparison between the biochemical properties of plasma chitotriosidase from normal individuals and from patients with Gaucher disease, GM1-gangliosidosis, Krabbe disease and heterozygotes for ..." in: Clinical biochemistry, Vol. 40, Issue 5-6, pp. 365-9, (2007) (PubMed).

    Bargagli, Margollicci, Perrone, Luddi, Perari, Bianchi, Refini, Grosso, Volterrani, Rottoli: "Chitotriosidase analysis in bronchoalveolar lavage of patients with sarcoidosis." in: Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG / World Association of Sarcoidosis and Other Granulomatous Disorders, Vol. 24, Issue 1, pp. 59-64, (2007) (PubMed).

  • 抗原
    Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
    别名
    CHIT1 (CHIT1 产品)
    别名
    CHI3 antibody, CHIT antibody, CHITD antibody, CHIT1 antibody, chio antibody, 2300002L19Rik antibody, chitinase 1 antibody, chitinase 1 (chitotriosidase) antibody, CHIT1 antibody, chit1 antibody, Chit1 antibody
    背景

    Description: CHIT1:chitinase 1 (chitotriosidase). Chitotriosidase is a 50 kDa secreted glycoprotein that belongs to glycohydrolase family # 18. It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.

    Aliases: Chitotriosidase,CHI3, CHIT, FLJ00314, MGC125322, CHIT1

    分子量
    52kDa
    基因ID
    1118
    HGNC
    1118
    UniProt
    Q13231
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