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N-Cadherin 抗体

CDH2 适用: 人 WB, IHC, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 5D5 unconjugated
产品编号 ABIN969038
发货至: 中国
  • 抗原 See all N-Cadherin (CDH2) 抗体
    N-Cadherin (CDH2) (Cadherin 2 (CDH2))
    适用
    • 138
    • 92
    • 67
    • 21
    • 16
    • 14
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    • 4
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    宿主
    • 92
    • 53
    • 4
    • 4
    • 2
    小鼠
    克隆类型
    • 85
    • 70
    单克隆
    标记
    • 80
    • 15
    • 5
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This N-Cadherin antibody is un-conjugated
    应用范围
    • 110
    • 52
    • 39
    • 38
    • 24
    • 22
    • 17
    • 14
    • 13
    • 12
    • 12
    • 8
    • 4
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    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)
    原理
    CDH2 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human CDH2 expressed in E. Coli.
    克隆位点
    5D5
    亚型
    IgG1
    Top Product
    Discover our top product CDH2 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Wallerand, Cai, Wainberg, Garraway, Lascombe, Nicolle, Thiery, Bittard, Radvanyi, Reiter: "Phospho-Akt pathway activation and inhibition depends on N-cadherin or phospho-EGFR expression in invasive human bladder cancer cell lines." in: Urologic oncology, Vol. 28, Issue 2, pp. 180-8, (2010) (PubMed).

    Sharma, Henderson: "IQ-domain GTPase-activating protein 1 regulates beta-catenin at membrane ruffles and its role in macropinocytosis of N-cadherin and adenomatous polyposis coli." in: The Journal of biological chemistry, Vol. 282, Issue 11, pp. 8545-56, (2007) (PubMed).

  • 抗原
    N-Cadherin (CDH2) (Cadherin 2 (CDH2))
    别名
    CDH2 (CDH2 产品)
    别名
    CD325 antibody, CDHN antibody, CDw325 antibody, NCAD antibody, N-cadherin antibody, cadherin-2 antibody, cdhn antibody, ncad antibody, cdw325 antibody, CDH2 antibody, Cadherin-2 antibody, Ncad antibody, glo antibody, lyr antibody, pac antibody, wu:fb47h04 antibody, cadherin 2 antibody, cadherin 2 S homeolog antibody, cadherin 2, type 1, N-cadherin (neuronal) antibody, CDH2 antibody, cdh2.S antibody, cdh2 antibody, Cdh2 antibody
    背景

    Description: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.

    Aliases: CDHN, NCAD, CD325, CDw325, CDH2

    分子量
    99.8kDa
    基因ID
    1000
    HGNC
    1000
    UniProt
    P19022
    途径
    Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane
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