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- 抗原 See all CD40 抗体
- CD40
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD40 antibody is un-conjugated
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应用范围
- ELISA, Immunocytochemistry (ICC)
- 原理
- CD40 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of CD40 expressed in E. Coli.
- 克隆位点
- 9G10
- 亚型
- IgG1
- Top Product
- Discover our top product CD40 Primary Antibody
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- 应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Immunohistochemical expression of CD23 and CD40 may identify prognostically favorable subgroups of diffuse large B-cell lymphoma: a Nordic Lymphoma Group Study." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 9, Issue 2, pp. 722-8, (2003) (PubMed).
: "CD40 is expressed on ovarian cancer cells and can be utilized for targeting adenoviruses." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 9, Issue 2, pp. 619-24, (2003) (PubMed).
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Immunohistochemical expression of CD23 and CD40 may identify prognostically favorable subgroups of diffuse large B-cell lymphoma: a Nordic Lymphoma Group Study." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 9, Issue 2, pp. 722-8, (2003) (PubMed).
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- 抗原
- CD40
- 别名
- CD40 (CD40 产品)
- 别名
- Bp50 antibody, CDW40 antibody, TNFRSF5 antibody, p50 antibody, AI326936 antibody, GP39 antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TRAP antibody, Tnfrsf5 antibody, TNFSF5 antibody, CD40 molecule antibody, CD40 antigen antibody, CD40 antibody, Cd40 antibody
- 背景
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Description: CD40 Molecule, TNF receptor superfamily member 5. It is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Aliases: p50, Bp50, CDW40, TNFRSF5
- 分子量
- 30.6kDa
- 基因ID
- 958
- HGNC
- 958
- UniProt
- P25942
- 途径
- NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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