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CD40 抗体

CD40 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 9G10 unconjugated
产品编号 ABIN969025
发货至: 中国
  • 抗原 See all CD40 抗体
    CD40
    适用
    • 179
    • 97
    • 20
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    • 6
    • 6
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    • 1
    宿主
    • 99
    • 95
    • 43
    • 5
    • 1
    • 1
    • 1
    小鼠
    克隆类型
    • 148
    • 90
    • 5
    单克隆
    标记
    • 117
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    This CD40 antibody is un-conjugated
    应用范围
    • 143
    • 92
    • 59
    • 47
    • 30
    • 28
    • 20
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    • 14
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    ELISA, Immunocytochemistry (ICC)
    原理
    CD40 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of CD40 expressed in E. Coli.
    克隆位点
    9G10
    亚型
    IgG1
    Top Product
    Discover our top product CD40 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Linderoth, Jerkeman, Cavallin-Ståhl, Kvaløy, Torlakovic: "Immunohistochemical expression of CD23 and CD40 may identify prognostically favorable subgroups of diffuse large B-cell lymphoma: a Nordic Lymphoma Group Study." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 9, Issue 2, pp. 722-8, (2003) (PubMed).

    Hakkarainen, Hemminki, Pereboev, Barker, Asiedu, Strong, Kanerva, Wahlfors, Curiel: "CD40 is expressed on ovarian cancer cells and can be utilized for targeting adenoviruses." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 9, Issue 2, pp. 619-24, (2003) (PubMed).

  • 抗原
    CD40
    别名
    CD40 (CD40 产品)
    别名
    Bp50 antibody, CDW40 antibody, TNFRSF5 antibody, p50 antibody, AI326936 antibody, GP39 antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TRAP antibody, Tnfrsf5 antibody, TNFSF5 antibody, CD40 molecule antibody, CD40 antigen antibody, CD40 antibody, Cd40 antibody
    背景

    Description: CD40 Molecule, TNF receptor superfamily member 5. It is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

    Aliases: p50, Bp50, CDW40, TNFRSF5

    分子量
    30.6kDa
    基因ID
    958
    HGNC
    958
    UniProt
    P25942
    途径
    NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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