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- 抗原 See all CD276 抗体
- CD276
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD276 antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC)
- 原理
- CD276 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human CD276 expressed in E. Coli.
- 克隆位点
- 6A1
- 亚型
- IgG1
- Top Product
- Discover our top product CD276 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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B7-H3: another molecule marker for Mo-DCs?" in: Cellular & molecular immunology, Vol. 2, Issue 4, pp. 307-11, (2005) (PubMed).
: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).
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B7-H3: another molecule marker for Mo-DCs?" in: Cellular & molecular immunology, Vol. 2, Issue 4, pp. 307-11, (2005) (PubMed).
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- 抗原
- CD276
- 别名
- CD276 (CD276 产品)
- 别名
- sc:d0645 antibody, zgc:158279 antibody, 6030411F23Rik antibody, AU016588 antibody, B7RP-2 antibody, B7h3 antibody, B7H3 antibody, 4Ig-B7-H3 antibody, B7-H3 antibody, CD276 molecule antibody, CD276 molecule S homeolog antibody, CD276 antigen antibody, Cd276 molecule antibody, CD276 antibody, cd276.S antibody, cd276 antibody, Cd276 antibody
- 背景
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Description: Costimulatory B7 Molecules (e.g., B7-1, or CD80, MIM 112203) signal through CD28 (MIM 186760) family molecules such as CD28, CTLA4 (MIM 123890), and ICOS (MIM 604558). May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.
Aliases: B7H3, B7-H3, 4Ig-B7-H3, CD276
- 分子量
- 57kDa
- 基因ID
- 80381
- HGNC
- 80381
- UniProt
- Q5ZPR3
- 途径
- Cancer Immune Checkpoints
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