CBL 抗体
(3 references)-
- 抗原 See all CBL 抗体
- CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This CBL antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 原理
- C-CBL Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human C-CBL expressed in E. Coli.
- 克隆位点
- 3B12
- 亚型
- IgG1
-
anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (AA 736-835) antibody
CBL 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 6D12 unconjugated
anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (AA 1-906) antibodyCBL 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (AA 1-906) antibodyCBL 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (Internal Region) antibodyCBL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (AA 548-847) antibodyCBL 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (pTyr770) antibodyCBL 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) antibodyCBL 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (pTyr674) antibodyCBL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (AA 637-906) antibodyCBL 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (pTyr674) antibodyCBL 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
: "Cbl negatively regulates JNK activation and cell death." in: Cell research, Vol. 19, Issue 8, pp. 950-61, (2009) (PubMed).
: "Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms. ..." in: Nature, Vol. 460, Issue 7257, pp. 904-8, (2009) (PubMed).
: "Mutations in CBL occur frequently in juvenile myelomonocytic leukemia. ..." in: Blood, Vol. 114, Issue 9, pp. 1859-63, (2009) (PubMed).
-
: "Cbl negatively regulates JNK activation and cell death." in: Cell research, Vol. 19, Issue 8, pp. 950-61, (2009) (PubMed).
-
- 抗原
- CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))
- 别名
- C-CBL (CBL 产品)
- 别名
- 4732447J05Rik antibody, Cbl-2 antibody, c-Cbl antibody, cbl antibody, C-CBL antibody, CBL2 antibody, FRA11B antibody, NSLL antibody, RNF55 antibody, c-cbl-like antibody, RGD1561386 antibody, Casitas B-lineage lymphoma antibody, Cbl proto-oncogene antibody, Cbl antibody, CBL antibody
- 背景
-
Description: The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation.
Aliases: CBL, CBL2, NSLL, C-CBL, RNF55
- 分子量
- 120kDa
- 基因ID
- 867
- HGNC
- 867
- UniProt
- P22681
- 途径
- TCR Signaling, Interferon-gamma Pathway, EGFR Signaling Pathway, EGFR Downregulation, VEGFR1 Specific Signals
-
