(2 references)-
- 抗原 See all BMX 抗体
- BMX (BMX Non-Receptor Tyrosine Kinase (BMX))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This BMX antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human BMX expressed in E. coli.
- 克隆位点
- 1C6
- 亚型
- IgG1
- Top Product
- Discover our top product BMX Primary Antibody
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anti-BMX Non-Receptor Tyrosine Kinase (BMX) (AA 287-523) antibody
BMX 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (C-Term) antibodyBMX 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (N-Term) antibodyBMX 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (AA 65-280) antibodyBMX 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (AA 150-280) antibodyBMX 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G3 unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (pTyr566) antibodyBMX 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (pTyr566) antibodyBMX 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (AA 65-280) antibodyBMX 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (AA 209-446) antibodyBMX 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (N-Term) antibodyBMX 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IP, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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: "Bmx tyrosine kinase regulates TLR4-induced IL-6 production in human macrophages independently of p38 MAPK and NFkapp}B activity." in: Blood, Vol. 111, Issue 4, pp. 1781-8, (2008) (PubMed).
: "A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling." in: Nature cell biology, Vol. 7, Issue 8, pp. 797-807, (2005) (PubMed).
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: "Bmx tyrosine kinase regulates TLR4-induced IL-6 production in human macrophages independently of p38 MAPK and NFkapp}B activity." in: Blood, Vol. 111, Issue 4, pp. 1781-8, (2008) (PubMed).
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- 抗原
- BMX (BMX Non-Receptor Tyrosine Kinase (BMX))
- 别名
- BMX (BMX 产品)
- 别名
- BMX antibody, ETK antibody, PSCTK2 antibody, PSCTK3 antibody, Etk antibody, Etk/Bmx antibody, Tyro8 antibody, RGD1565643 antibody, BMX non-receptor tyrosine kinase antibody, BMX antibody, bmx antibody, Bmx antibody
- 背景
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Description: BMX (bone marrow X kinase) is a cytoplasmic tyrosine kinase identified by reverse transcription of mRNA isolated from human bone marrow and mapped to the chromosomal band Xp22.2. The full length protein is 675 amino acids with a tyrosine kinase domain, an amino terminal pleckstrin domain, as well as an SH3 and SH2 domain. Direct comparison of BMX's primary sequence with other kinases showed that this is highly related to the family of BTK/ITK/TEC. BMX kinase is expressed in fetal and adult tissues, with the highest expression in heart, testis, small intestine and colon. It is undetectable in spleen, brain, kidney, and pancreas. Further analysis of mRNA expression showed that BMX is expressed in hematopoietic tissues and neutrophilic granulocytes, and in patients with acute and myeloid leukemia. The levels of BMX mRNA were substantially lower in patients with acute and chronic lymphoid leukemias, thus suggesting that BMX may be important during myelopoiesis.CST:It is expressed in a variety of hematopoietic, epithelial and endothelial cells.
Aliases: ETK, PSCTK2, PSCTK3, BMX
- 分子量
- 78 kDa
- 基因ID
- 660
- HGNC
- 660
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