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BMI1 抗体

BMI1 适用: 人 ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 3E3 unconjugated
产品编号 ABIN968985
发货至: 中国
  • 抗原 See all BMI1 抗体
    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
    适用
    • 111
    • 47
    • 27
    • 11
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 78
    • 31
    • 6
    小鼠
    克隆类型
    • 81
    • 34
    单克隆
    标记
    • 75
    • 9
    • 9
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BMI1 antibody is un-conjugated
    应用范围
    • 92
    • 50
    • 42
    • 20
    • 12
    • 12
    • 11
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    原理
    BMI1 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human BMI1 expressed in E. Coli.
    克隆位点
    3E3
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Edwards, Witherspoon, Wang, Afrasiabi, Pham, Birnbaumer, Lipkin: "Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer." in: Cancer research, Vol. 69, Issue 16, pp. 6423-9, (2009) (PubMed).

    Bhattacharya, Nicoloso, Arvizo, Wang, Cortez, Rossi, Calin, Mukherjee: "MiR-15a and MiR-16 control Bmi-1 expression in ovarian cancer." in: Cancer research, Vol. 69, Issue 23, pp. 9090-5, (2009) (PubMed).

  • 抗原
    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
    别名
    BMI1 (BMI1 产品)
    别名
    FLVI2/BMI1 antibody, PCGF4 antibody, RNF51 antibody, AW546694 antibody, Bmi-1 antibody, Pcgf4 antibody, bmi1 antibody, pcgf4 antibody, psc1 antibody, wu:fb17g03 antibody, wu:fd18f06 antibody, BMI-1 antibody, pcgf4b antibody, bmi-1 antibody, bmi1-a antibody, bmi1-b antibody, bmi1b antibody, rnf51 antibody, xbmi-1 antibody, BMI1 proto-oncogene, polycomb ring finger antibody, BMI1 polycomb ring finger oncogene antibody, Bmi1 polycomb ring finger oncogene antibody, bmi1 polycomb ring finger oncogene 1a antibody, bmi1 polycomb ring finger oncogene 1b antibody, BMI1 proto-oncogene, polycomb ring finger L homeolog antibody, BMI1 antibody, LOC100230513 antibody, Bmi1 antibody, bmi1a antibody, bmi1b antibody, bmi1.L antibody
    背景

    Description: Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

    Aliases: PCGF4, RNF51, MGC12685, FLVI2/BMI1

    分子量
    37kDa
    基因ID
    648
    HGNC
    648
    UniProt
    P35226
    途径
    Cell Division Cycle, Autophagy
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