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BLK 抗体

BLK 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 9D10B7 unconjugated
产品编号 ABIN968981
发货至: 中国
  • 抗原 See all BLK 抗体
    BLK (B Lymphoid Tyrosine Kinase (BLK))
    适用
    • 66
    • 24
    • 15
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    • 1
    • 1
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    宿主
    • 54
    • 9
    • 1
    小鼠
    克隆类型
    • 56
    • 10
    单克隆
    标记
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    • 2
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    This BLK antibody is un-conjugated
    应用范围
    • 50
    • 37
    • 28
    • 13
    • 13
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    原理
    BLK Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of BLK expressed in E. Coli.
    克隆位点
    9D10B7
    亚型
    IgG1
    Top Product
    Discover our top product BLK Primary Antibody
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Tretter, Ross, Dordai, Desiderio: "Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk." in: The Journal of experimental medicine, Vol. 198, Issue 12, pp. 1863-73, (2003) (PubMed).

  • 抗原
    BLK (B Lymphoid Tyrosine Kinase (BLK))
    别名
    BLK (BLK 产品)
    别名
    bltk antibody, si:dkey-33i22.2 antibody, zgc:136231 antibody, MODY11 antibody, BLK proto-oncogene, Src family tyrosine kinase antibody, B lymphoid kinase antibody, blk antibody, BLK antibody, Blk antibody
    背景

    Description: BLK ( B lymphoid tyrosine kinase), with 505-amino acid protein (about 56KDa), belongs to the Src non-receptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.

    Aliases: MGC10442

    基因ID
    640
    HGNC
    640
    UniProt
    P51451
    途径
    Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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