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AXL 抗体

AXL 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 7E10 unconjugated
产品编号 ABIN968974
发货至: 中国
  • 抗原 See all AXL 抗体
    AXL (AXL Receptor tyrosine Kinase (AXL))
    适用
    • 136
    • 73
    • 67
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    宿主
    • 125
    • 17
    • 3
    • 1
    小鼠
    克隆类型
    • 125
    • 21
    单克隆
    标记
    • 55
    • 10
    • 9
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This AXL antibody is un-conjugated
    应用范围
    • 104
    • 58
    • 29
    • 26
    • 26
    • 17
    • 13
    • 9
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunocytochemistry (ICC)
    原理
    AXL Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant extracellular fragment of human AXL fused with hIgGFc tag expressed in HEK293 cell line.
    克隆位点
    7E10
    亚型
    IgG1
    Top Product
    Discover our top product AXL Primary Antibody
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Vajkoczy, Knyazev, Kunkel, Capelle, Behrndt, von Tengg-Kobligk, Kiessling, Eichelsbacher, Essig, Read, Erber, Ullrich: "Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 15, pp. 5799-804, (2006) (PubMed).

  • 抗原
    AXL (AXL Receptor tyrosine Kinase (AXL))
    别名
    AXL (AXL 产品)
    别名
    JTK11 antibody, UFO antibody, AI323647 antibody, Ark antibody, Tyro7 antibody, Ufo antibody, AXL receptor tyrosine kinase antibody, Axl receptor tyrosine kinase antibody, AXL antibody, Axl antibody
    背景

    Description: AXL: AXL receptor tyrosine kinase, also known as UFO, JTK11. Entrez Protein NP_001690. It is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.

    Aliases: UFO, JTK11

    分子量
    97.4kDa
    基因ID
    558
    HGNC
    558
    UniProt
    P30530
    途径
    RTK signaling, Cellular Response to Molecule of Bacterial Origin
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