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- 抗原 See all APOB 抗体
- APOB (Apolipoprotein B (APOB))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This APOB antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human ApoB expressed in E. coli.
- 克隆位点
- 6G6
- 亚型
- IgG1
- Top Product
- Discover our top product APOB Primary Antibody
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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Apolipoprotein B levels, APOB alleles, and risk of ischemic cardiovascular disease in the general population, a review." in: Atherosclerosis, Vol. 206, Issue 1, pp. 17-30, (2009) (PubMed).
: "Apolipoprotein B Is an innate barrier against invasive Staphylococcus aureus infection." in: Cell host & microbe, Vol. 4, Issue 6, pp. 555-66, (2008) (PubMed).
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Apolipoprotein B levels, APOB alleles, and risk of ischemic cardiovascular disease in the general population, a review." in: Atherosclerosis, Vol. 206, Issue 1, pp. 17-30, (2009) (PubMed).
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- 抗原
- APOB (Apolipoprotein B (APOB))
- 别名
- ApoB (APOB 产品)
- 别名
- FLDB antibody, LDLCQ4 antibody, Ac1-060 antibody, Apo B-100 antibody, ApoB-100 antibody, ApoB-48 antibody, AI315052 antibody, apob-100 antibody, apob-48 antibody, APOB-100 antibody, ApoB(100) antibody, APOB antibody, apolipoprotein B antibody, APOB antibody, Apob antibody
- 背景
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Description: This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.
Aliases: FLDB, LDLCQ4
- 分子量
- 516 kDa
- 基因ID
- 338
- HGNC
- 338
- 途径
- Lipid Metabolism
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