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AMACR 抗体

AMACR 适用: 人 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 2A10F3 unconjugated
产品编号 ABIN968957
发货至: 中国
  • 抗原 See all AMACR 抗体
    AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
    适用
    • 100
    • 16
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 65
    • 35
    • 2
    小鼠
    克隆类型
    • 54
    • 48
    单克隆
    标记
    • 58
    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AMACR antibody is un-conjugated
    应用范围
    • 68
    • 51
    • 38
    • 35
    • 18
    • 16
    • 13
    • 10
    • 7
    • 6
    • 6
    • 5
    • 3
    • 1
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    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
    原理
    AMACR Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human AMACR expressed in E. Coli.
    克隆位点
    2A10F3
    亚型
    IgG2b
    Top Product
    Discover our top product AMACR Primary Antibody
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Chen, Watson, Marengo, Decker, Coleman, Nelson, Sikes: "Gene expression in the LNCaP human prostate cancer progression model: progression associated expression in vitro corresponds to expression changes associated with prostate cancer progression in vivo." in: Cancer letters, Vol. 244, Issue 2, pp. 274-88, (2006) (PubMed).

    Epstein, Herawi: "Prostate needle biopsies containing prostatic intraepithelial neoplasia or atypical foci suspicious for carcinoma: implications for patient care." in: The Journal of urology, Vol. 175, Issue 3 Pt 1, pp. 820-34, (2006) (PubMed).

  • 抗原
    AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
    别名
    AMACR (AMACR 产品)
    别名
    AMACR antibody, DKFZp469O1232 antibody, amacr antibody, NCU04099.1 antibody, MGC89832 antibody, AMACRD antibody, CBAS4 antibody, RACE antibody, RM antibody, Macr1 antibody, Da1-8 antibody, Marc1 antibody, alpha-methylacyl-CoA racemase antibody, PROBABLE ALPHA-METHYLACYL-COA RACEMASE MCR (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase) antibody, Alpha-methylacyl-CoA racemase antibody, alpha-methylacyl-CoA racemase L homeolog antibody, AMACR antibody, mcr antibody, BPSL0064 antibody, Maqu_2037 antibody, UREG_03852 antibody, MCYG_01809 antibody, amacr antibody, amacr.L antibody, MGYG_04259 antibody, NCU04099 antibody, Amacr antibody
    背景

    Description: AMACR (alpha-methylacyl-CoA racemase) has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMACR protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. AMACR can be used as a positive marker for PIN. Defects in AMACR are the cause of congenital bile acid synthesis defect type 4 (CBAS4), also known as cholestasis, intrahepatic, with defective conversion of trihydroxycoprostanic acid to cholic acid or trihydroxycoprostanic acid in bile. Clinical features include neonatal jaundice, intrahepatic cholestasis, bile duct deficiency and absence of cholic acid from bile.

    Aliases: RACE

    分子量
    42kDa
    基因ID
    23600
    HGNC
    23600
    UniProt
    Q9UHK6
    途径
    Monocarboxylic Acid Catabolic Process
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