AMACR 抗体
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- 抗原 See all AMACR 抗体
- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This AMACR antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
- 原理
- AMACR Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human AMACR expressed in E. Coli.
- 克隆位点
- 2A10F3
- 亚型
- IgG2b
- Top Product
- Discover our top product AMACR Primary Antibody
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- 应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Gene expression in the LNCaP human prostate cancer progression model: progression associated expression in vitro corresponds to expression changes associated with prostate cancer progression in vivo." in: Cancer letters, Vol. 244, Issue 2, pp. 274-88, (2006) (PubMed).
: "Prostate needle biopsies containing prostatic intraepithelial neoplasia or atypical foci suspicious for carcinoma: implications for patient care." in: The Journal of urology, Vol. 175, Issue 3 Pt 1, pp. 820-34, (2006) (PubMed).
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Gene expression in the LNCaP human prostate cancer progression model: progression associated expression in vitro corresponds to expression changes associated with prostate cancer progression in vivo." in: Cancer letters, Vol. 244, Issue 2, pp. 274-88, (2006) (PubMed).
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- 抗原
- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
- 别名
- AMACR (AMACR 产品)
- 别名
- AMACR antibody, DKFZp469O1232 antibody, amacr antibody, NCU04099.1 antibody, MGC89832 antibody, AMACRD antibody, CBAS4 antibody, RACE antibody, RM antibody, Macr1 antibody, Da1-8 antibody, Marc1 antibody, alpha-methylacyl-CoA racemase antibody, PROBABLE ALPHA-METHYLACYL-COA RACEMASE MCR (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase) antibody, Alpha-methylacyl-CoA racemase antibody, alpha-methylacyl-CoA racemase L homeolog antibody, AMACR antibody, mcr antibody, BPSL0064 antibody, Maqu_2037 antibody, UREG_03852 antibody, MCYG_01809 antibody, amacr antibody, amacr.L antibody, MGYG_04259 antibody, NCU04099 antibody, Amacr antibody
- 背景
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Description: AMACR (alpha-methylacyl-CoA racemase) has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMACR protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. AMACR can be used as a positive marker for PIN. Defects in AMACR are the cause of congenital bile acid synthesis defect type 4 (CBAS4), also known as cholestasis, intrahepatic, with defective conversion of trihydroxycoprostanic acid to cholic acid or trihydroxycoprostanic acid in bile. Clinical features include neonatal jaundice, intrahepatic cholestasis, bile duct deficiency and absence of cholic acid from bile.
Aliases: RACE
- 分子量
- 42kDa
- 基因ID
- 23600
- HGNC
- 23600
- UniProt
- Q9UHK6
- 途径
- Monocarboxylic Acid Catabolic Process
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