AIF 抗体
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- 抗原 See all AIF (AIFM1) 抗体
- AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This AIF antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 原理
- AIF Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human AIF expressed in E. Coli.
- 克隆位点
- 4E7
- 亚型
- IgG2b
- Top Product
- Discover our top product AIFM1 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Apoptosis-inducing factor plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells." in: Apoptosis : an international journal on programmed cell death, Vol. 14, Issue 6, pp. 796-808, (2009) (PubMed).
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Apoptosis-inducing factor plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells." in: Apoptosis : an international journal on programmed cell death, Vol. 14, Issue 6, pp. 796-808, (2009) (PubMed).
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- 抗原
- AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
- 别名
- AIF (AIFM1 产品)
- 背景
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Description: This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10
Aliases: AIFM1, AIF, PDCD8, COXPD6, MGC111425
- 分子量
- 67kDa
- 基因ID
- 9131
- HGNC
- 9131
- UniProt
- O95831
- 途径
- Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Warburg Effect
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