(2 references)-
- 抗原 See all ABL2 抗体
- ABL2
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ABL2 antibody is un-conjugated
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应用范围
- ELISA, Immunocytochemistry (ICC)
- 原理
- ABL2 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of ABL2 expressed in E. Coli.
- 克隆位点
- 1H1
- 亚型
- IgG1
- Top Product
- Discover our top product ABL2 Primary Antibody
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anti-ABL2 (ABL2) (AA 743-842) antibody
ABL2 适用: 人 WB, ELISA, PLA, RNAi 宿主: 小鼠 Monoclonal 6D5 unconjugated
anti-ABL2 (ABL2) (AA 743-842) antibodyABL2 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 5C6 unconjugated
anti-ABL2 (ABL2) antibodyABL2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1H1B11 unconjugated
anti-ABL2 (ABL2) (pTyr393), (pTyr439) antibodyABL2 适用: 人 WB, IHC (p), DB 宿主: 兔 Polyclonal RB7532 unconjugated
anti-ABL2 (ABL2) antibodyABL2 适用: 人, 小鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 2C3 unconjugated
anti-ABL2 (ABL2) (AA 1011-1044), (C-Term) antibodyABL2 适用: 小鼠 WB 宿主: 兔 Polyclonal RB50829 unconjugated
anti-ABL2 (ABL2) (AA 862-1064) antibodyABL2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ABL2 (ABL2) antibodyABL2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ABL2 (ABL2) (AA 1-1167) antibodyABL2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-ABL2 (ABL2) (Tyr251) antibodyABL2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Tyrosine kinase oncogenes in normal hematopoiesis and hematological disease." in: Oncogene, Vol. 21, Issue 21, pp. 3314-33, (2002) (PubMed).
: "A new ETV6/TEL partner gene, ARG (ABL-related gene or ABL2), identified in an AML-M3 cell line with a t(1;12)(q25;p13) translocation." in: Blood, Vol. 95, Issue 6, pp. 2126-31, (2000) (PubMed).
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: "Tyrosine kinase oncogenes in normal hematopoiesis and hematological disease." in: Oncogene, Vol. 21, Issue 21, pp. 3314-33, (2002) (PubMed).
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- 抗原
- ABL2
- 别名
- ABL2 (ABL2 产品)
- 别名
- ABLL antibody, ARG antibody, Abll antibody, Arg antibody, AA536808 antibody, ABL proto-oncogene 2, non-receptor tyrosine kinase antibody, v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene) antibody, ABL2 antibody, Abl2 antibody
- 背景
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Description: ABL2 (ARG, Abl-related gene), together with c-Abl, forms the Abl family of mammalian non-receptor tyrosine kinases. ABL2 and c-Abl share 89 % , 90 and 93 % identity in their SH3, SH2 and tyrosine domain, but only 29 % identity in the carboxy-terminal half. The human c-Abl and ABL2 genes are expressed ubiquitously. ABL2 had been detected predominantly in the cytoplasm, whereas c-Abl shows both cytoplasmic and nuclear localization. c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl. Recently, TEL-ARG fusion transcripts have also been identified in acute myeloid leukemias (AML). The Abl family kinases may also interact with receptor tyrosine signaling pathways and regulate cellular function such as cell cycle progression, gene transcription and organization of the actin cytoskeletons in neurons.
Aliases: ARG, ABLL, FLJ22224, FLJ31718, FLJ41441
- 分子量
- 128kDa
- 基因ID
- 27
- HGNC
- 27
- UniProt
- P42684
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