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SLU7 抗体 (AA 457-570)

SLU7 适用: 人, 小鼠, 大鼠, 犬, 小鸡 WB, IF 宿主: 小鼠 Monoclonal 35-hSlu7 unconjugated
产品编号 ABIN968890
发货至: 中国
  • 抗原 See all SLU7 抗体
    SLU7 (SLU7 Splicing Factor Homolog (SLU7))
    抗原表位
    • 15
    • 8
    • 8
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 457-570
    适用
    • 54
    • 13
    • 11
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 小鸡
    宿主
    • 50
    • 5
    小鼠
    克隆类型
    • 51
    • 4
    单克隆
    标记
    • 27
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLU7 antibody is un-conjugated
    应用范围
    • 50
    • 29
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    交叉反应
    犬, 大鼠, 小鼠
    无交叉反应
    小鸡
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Human hSlu7 aa. 457-570
    克隆位点
    35-hSlu7
    亚型
    IgG2b
    Top Product
    Discover our top product SLU7 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20° C.
  • Chua, Reed: "The RNA splicing factor hSlu7 is required for correct 3' splice-site choice." in: Nature, Vol. 402, Issue 6758, pp. 207-10, (2000) (PubMed).

    Chua, Reed: "Human step II splicing factor hSlu7 functions in restructuring the spliceosome between the catalytic steps of splicing." in: Genes & development, Vol. 13, Issue 7, pp. 841-50, (1999) (PubMed).

  • 抗原
    SLU7 (SLU7 Splicing Factor Homolog (SLU7))
    别名
    hSlu7 (SLU7 产品)
    别名
    9G8 antibody, hSlu7 antibody, AU018913 antibody, D11Ertd730e antibody, D3Bwg0878e antibody, 9g8 antibody, hslu7 antibody, wu:fc94e11 antibody, zgc:103640 antibody, CG1420 antibody, Dmel\\CG1420 antibody, SLU7 antibody, SLU7 homolog, splicing factor antibody, SLU7 splicing factor homolog (S. cerevisiae) antibody, SLU7 homolog, splicing factor L homeolog antibody, CG1420 gene product from transcript CG1420-RA antibody, SLU7 antibody, Slu7 antibody, slu7.L antibody, slu7 antibody
    物质类
    Influenza Protein
    背景
    Splicing, the removal of introns from pre-mRNA, is mediated by spliceosomal complexes and occurs in two distinct catalytic steps. The first step involves cleavage of the 5' exon and the production of a lariat intermediate. In the second step, the 3' splice site is cleaved and the exons are fused with concomitant release of the intron lariat. The spliceosome contains multiple snRNPs and a number of non-snRNP splicing factors. Four yeast proteins (Prp16p, Prp17p, Prp18p, and Slu7p) function exclusively in the second catalytic step. Human homologs have been identified for Prp16p (hPrp16), Prp17p (hPrp17), Prp18p (hPrp18) and Slu7 (hSlu7). hSlu7 contains a zinc knuckle motif similar to the yeast Slu7. This domain is present in retroviral nucleocapsid proteins and in several splicing factors. hSlu7 associates with the spliceosome late in the splicing pathway during recognition of the 3' splice site. During step II of 3' splicing, hSlu7 tightly binds to exon 1 in the spliceosome and helps specify attack on the correct adenine-guanine dinucleotide, located 18 to 40 nucleotides downstream of the branch site.
    分子量
    80 kDa
    途径
    Ribonucleoprotein Complex Subunit Organization, SARS-CoV-2 Protein Interactome
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