HNF1B 抗体 (AA 1-101)
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- 抗原 See all HNF1B 抗体
- HNF1B (HNF1 Homeobox B (HNF1B))
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抗原表位
- AA 1-101
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适用
- 人, 小鼠, 大鼠, 犬
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This HNF1B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 交叉反应
- 大鼠, 人, 犬
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Mouse HNF-1beta aa. 1-101
- 克隆位点
- 25-HNF
- 亚型
- IgG1
- Top Product
- Discover our top product HNF1B Primary Antibody
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anti-HNF1 Homeobox B (HNF1B) (AA 29-118) antibody
HNF1B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E9 unconjugated
anti-HNF1 Homeobox B (HNF1B) (AA 29-118) antibodyHNF1B 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3H4 unconjugated
anti-HNF1 Homeobox B (HNF1B) (N-Term) antibodyHNF1B 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 马, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-HNF1 Homeobox B (HNF1B) (AA 159-300) antibodyHNF1B 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-HNF1 Homeobox B (HNF1B) (AA 1-557) antibodyHNF1B 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-HNF1 Homeobox B (HNF1B) (AA 539-704) antibodyHNF1B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-HNF1 Homeobox B (HNF1B) (Internal Region) antibodyHNF1B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-HNF1 Homeobox B (HNF1B) (Internal Region) antibodyVerified HNF1B 适用: 人, 小鼠 WB, ELISA, ICC 宿主: 山羊 Polyclonal unconjugated
anti-HNF1 Homeobox B (HNF1B) (AA 100-200) antibodyHNF1B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-HNF1 Homeobox B (HNF1B) (C-Term) antibodyHNF1B 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 兔, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN968547, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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: "Role of tissue-specific transcription factor LFB3 in a cyclic AMP-responsive enhancer of the urokinase-type plasminogen activator gene in LLC-PK1 cells." in: Molecular and cellular biology, Vol. 18, Issue 8, pp. 4698-706, (1998) (PubMed).
: "The transactivation potential of variant hepatocyte nuclear factor 1 is modified by alternative splicing." in: The Journal of biological chemistry, Vol. 268, Issue 34, pp. 25706-11, (1994) (PubMed).
: "LFB3, a heterodimer-forming homeoprotein of the LFB1 family, is expressed in specialized epithelia." in: The EMBO journal, Vol. 10, Issue 6, pp. 1435-43, (1991) (PubMed).
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: "Role of tissue-specific transcription factor LFB3 in a cyclic AMP-responsive enhancer of the urokinase-type plasminogen activator gene in LLC-PK1 cells." in: Molecular and cellular biology, Vol. 18, Issue 8, pp. 4698-706, (1998) (PubMed).
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- 抗原
- HNF1B (HNF1 Homeobox B (HNF1B))
- 别名
- HNF-1beta (HNF1B 产品)
- 别名
- FJHN antibody, HNF-1B antibody, HNF1beta antibody, HNF2 antibody, HPC11 antibody, LF-B3 antibody, LFB3 antibody, MODY5 antibody, TCF-2 antibody, TCF2 antibody, VHNF1 antibody, HNF-1b antibody, HNF1B antibody, AI385728 antibody, AI987804 antibody, HNF-1Beta antibody, Hnf1beta antibody, Tcf-2 antibody, Tcf2 antibody, vHNF1 antibody, vHNF-1 antibody, chunp6877 antibody, hnf1b antibody, mst antibody, tcf2 antibody, vhnf1 antibody, lfb3 antibody, hnf-1beta antibody, hnf1-beta antibody, hnf1beta antibody, HNF1g antibody, wu:fc23f06 antibody, HNF1 homeobox B antibody, HNF1 homeobox Ba antibody, HNF1 homeobox B S homeolog antibody, HNF1 homeobox B L homeolog antibody, HNF1 homeobox Bb antibody, HNF1B antibody, Hnf1b antibody, hnf1ba antibody, hnf1b.S antibody, hnf1b.L antibody, hnf1bb antibody
- 背景
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HNF's (Hepatocyte Nuclear Factor) are POU-homeodomain-containing liver enriched transcription factors that include HNF1-alpha, HNF1-beta, HNF-3alpha, HNF-3beta, HNF-4 and HNF-6. HNF-1 is expressed in liver, kidney, and intestine, while HNF-1beta is expressed highest in kidney with lower levels in intestine, lung, and liver. Both HNF-1 and HNF-1beta have short N-terminal alpha-helical segments that facilitate homodimerization (A-domain), a region related to POU-specific A-box (B-domain), and a homeodomain (C-domain). The HNF-1 and HNF-1beta homo- and hetero-dimers transactivate genes required for development of various tissues. Both transcription factors can bind the consensus HNF1 inverted palindromic sequence GTTAATNATTAAC. HNF-1 represses its own transcription and data suggests that there is coordinate regulation between HNF-1 and HNF-4. Although HNF-4 induces HNF-1 transcription, HNF-1 downregulates HNF-4 activity by binding to the AF2 region in the activation domain of HNF-4. Thus, HNF transcription factors may be involved in various aspects of the regulation of gene transcription throughout development.
Synonyms: Hepatocyte Nuclear Factor-1beta - 分子量
- 51 kDa
- 途径
- Hormone Transport, Stem Cell Maintenance, Tube Formation
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