SEC31A 抗体 (AA 522-719)
(2 references)-
- 抗原 See all SEC31A 抗体
- SEC31A (SEC31 Homolog A (SEC31A))
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抗原表位
- AA 522-719
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SEC31A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human Sec31A aa. 522-719
- 克隆位点
- 32-Sec31A
- 亚型
- IgG1
- Top Product
- Discover our top product SEC31A Primary Antibody
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anti-SEC31 Homolog A (SEC31A) (AA 429-571) antibody
SEC31A 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5D12C6 unconjugated
anti-SEC31 Homolog A (SEC31A) (AA 335-503) antibodySEC31A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SEC31 Homolog A (SEC31A) (AA 473-502) antibodySEC31A 适用: 小鼠 WB 宿主: 兔 Polyclonal RB41562 unconjugated
anti-SEC31 Homolog A (SEC31A) (AA 110-159) antibodySEC31A 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 兔, Bat, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-SEC31 Homolog A (SEC31A) (AA 300-500) antibodySEC31A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SEC31 Homolog A (SEC31A) (N-Term) antibodySEC31A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SEC31 Homolog A (SEC31A) antibodySEC31A 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-SEC31 Homolog A (SEC31A) (N-Term) antibodySEC31A 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN968537, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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: "A membrane protein enriched in endoplasmic reticulum exit sites interacts with COPII." in: The Journal of biological chemistry, Vol. 276, Issue 43, pp. 40008-17, (2001) (PubMed).
: "Mammalian homologues of yeast sec31p. An ubiquitously expressed form is localized to endoplasmic reticulum (ER) exit sites and is essential for ER-Golgi transport." in: The Journal of biological chemistry, Vol. 275, Issue 18, pp. 13597-604, (2000) (PubMed).
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: "A membrane protein enriched in endoplasmic reticulum exit sites interacts with COPII." in: The Journal of biological chemistry, Vol. 276, Issue 43, pp. 40008-17, (2001) (PubMed).
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- 抗原
- SEC31A (SEC31 Homolog A (SEC31A))
- 别名
- Sec31A (SEC31A 产品)
- 别名
- ABP125 antibody, ABP130 antibody, HSPC334 antibody, SEC31L1 antibody, Sec31l1 antibody, VAP1 antibody, 1810024J13Rik antibody, AU042160 antibody, HSPC275 antibody, cb354 antibody, sec31p antibody, zgc:63547 antibody, SEC31 homolog A, COPII coat complex component antibody, Sec31 homolog A (S. cerevisiae) antibody, SEC31A antibody, Sec31a antibody, sec31a antibody
- 背景
- Eukaryotic protein trafficking involves packaging of target molecules into membranous vesicles that bud from a donor compartment, travel to a specific destination, fuse, and release their contents into an acceptor compartment. Vesicles that bud from the Golgi cisternae and from the ER contain a non-clathrin based coat. This coat is an oligomeric complex whose subunits are termed COPs (coatomer proteins). COPI is the golgi- and endosome-associated COP complex, while COPII is the ER-associated coat complex. In yeast, the COPII complex has a cargo binding subcomplex that includes Sar1p, Sec23p, and Sec24p, which recruits Sec13p and Sec31p leading to vesicle formation. The human homologues of Sec31p are Sec31A and Sec31B. Sec31A has 40% identity with Sec31B, and contains an N-terminal WD-40 domain and a C-terminal proline-rich region. Sec31A mRNA is widely expressed, while Sec31B is found only in testis and thymus. In HeLa, Sec31A localizes to vesicular structures in the perinuclear region of the cell, and co-localizes with the COPII component Sec13. Antibodies against Sec31A inhibit ER to Golgi transport of vesicular stomatitis G protein. Thus, Sec31 may be an important COPII component involved in ER to Golgi transport, as well as a marker for COPII vesicles.
- 分子量
- 148 kDa
- 途径
- ER-Nucleus Signaling
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